Gammon W R, Wheeler C E
Arch Dermatol. 1979 Jan;115(1):76-80. doi: 10.1001/archderm.115.1.76.
A woman with cutaneous vasculitis had a severe bullous eruption that was suggestive of erythema multiforme. The patient also had a history of recurrent urticaria that continued intermittently for over a year of follow-up examination. Skin biopsy specimens of both urticarial and erythema and multiforme lesions showed leukocytoclastic vasculitis. An illness resembling systemic lupus erythematosus (SLE) is suggested by transient, low-titer, positive antinuclear antibody tests, persistent deposits of immunoglobulin and complement in normal skin, arthralgias, circulating immune complexes, and chronic hypocomplementemia. This case is similar to cases previously reported as "hypocomplementemic vasculitis," an "unusual SLE-related syndrome," and "urticaria with vasculitis."
一名患有皮肤血管炎的女性出现了严重的大疱性皮疹,提示多形红斑。该患者还有复发性荨麻疹病史,在长达一年的随访检查中荨麻疹间歇性发作。荨麻疹、红斑及多形红斑皮损的皮肤活检标本均显示白细胞破碎性血管炎。短暂的低滴度抗核抗体试验阳性、免疫球蛋白和补体在正常皮肤中的持续沉积、关节痛、循环免疫复合物以及慢性补体低下提示存在类似系统性红斑狼疮(SLE)的疾病。该病例与先前报道的“补体低下性血管炎”“一种不寻常的SLE相关综合征”以及“伴有血管炎的荨麻疹”病例相似。