Yoshinaga Shinji, Mabuchi Kiyohiko, Sigurdson Alice J, Doody Michele Morin, Ron Elaine
Radiation Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892, USA.
Radiology. 2004 Nov;233(2):313-21. doi: 10.1148/radiol.2332031119. Epub 2004 Sep 16.
Radiologists and radiologic technologists were among the earliest occupational groups exposed to ionizing radiation and represent a large segment of the working population exposed to radiation from human-made sources. The authors reviewed epidemiologic data on cancer risks from eight cohorts of over 270,000 radiologists and technologists in various countries. The most consistent finding was increased mortality due to leukemia among early workers employed before 1950, when radiation exposures were high. This, together with an increasing risk of leukemia with increasing duration of work in the early years, provided evidence of an excess risk of leukemia associated with occupational radiation exposure in that period. While findings on several types of solid cancers were less consistent, several studies provided evidence of a radiation effect for breast cancer and skin cancer. To date, there is no clear evidence of an increased cancer risk in medical radiation workers exposed to current levels of radiation doses. However, given a relatively short period of time for which the most recent workers have been followed up and in view of the increasing uses of radiation in modern medical practices, it is important to continue to monitor the health status of medical radiation workers.
放射科医生和放射技师是最早接触电离辐射的职业群体之一,并且在受人为来源辐射的工作人群中占很大比例。作者回顾了来自不同国家的超过27万名放射科医生和技师的八个队列的癌症风险流行病学数据。最一致的发现是,在1950年之前开始工作的早期从业者中,由于白血病导致的死亡率增加,当时辐射暴露水平很高。这一点,再加上早年工作时间越长白血病风险越高,为该时期职业辐射暴露与白血病额外风险之间的关联提供了证据。虽然关于几种实体癌的研究结果不太一致,但几项研究提供了辐射对乳腺癌和皮肤癌有影响的证据。迄今为止,没有明确证据表明接触当前辐射剂量水平的医学辐射工作者患癌风险增加。然而,鉴于对最近一批工作者的随访时间相对较短,并且考虑到现代医学实践中辐射使用的不断增加,持续监测医学辐射工作者的健康状况很重要。