Papathanasiou E S, Pantzaris M, Zamba-Papanicolaou E, Kyriakides T, Kleopa K A, Iliopoulos I, Piperidou C, Papacostas S
Department of Clinical Neurophysiology, The Cyprus Institute of Neurology & Genetics, 6 International Airport Avenue, PO.Box 23462, Nicosia 1683, Cyprus.
Electromyogr Clin Neurophysiol. 2004 Jul-Aug;44(5):313-7.
To determine the value of neurogenic vesibular evoked potential (NVESTEP) studies in comparison with other paraclinical tests in demonstrating dissemination in time and space in Multiple Sclerosis (MS) and in identifying clinically silent lesions.
All patients in whom MS was suspected but the diagnosis of MS was not possible based on the McDonald criteria were included in this study. We studied 14 patients and performed visual, brainstem auditory, somatosensory and neurogenic vestibular evoked potentials in all patients, together with MRI and CSF analysis of oligoclonal bands (OB).
Two out of the thirteen patients could be movedfrom the category of "possible MS" to "MS" using the McDonald criteria based on an abnormal NVESTEP result.
Neurogenic vestibular evoked potentials are potentially useful in identifying clinically silent lesions in patients with possible MS.
确定神经源性前庭诱发电位（NVESTEP）研究与其他临床旁检查相比，在显示多发性硬化症（MS）的时间和空间播散以及识别临床无症状病变方面的价值。
本研究纳入所有疑似MS但根据麦克唐纳标准无法确诊MS的患者。我们研究了14例患者，对所有患者进行了视觉、脑干听觉、体感和神经源性前庭诱发电位检查，同时进行了MRI和脑脊液寡克隆带（OB）分析。
根据异常的NVESTEP结果，使用麦克唐纳标准，13例患者中有2例可从“可能MS”类别转为“MS”类别。
神经源性前庭诱发电位在识别可能患有MS的患者的临床无症状病变方面可能有用。
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