Deslauriers Jean, Grégoire Jocelyn, Jacques Louis F, Piraux Michel
Department of Thoracic Surgery, Centre de Pneumologie de l'Hôpital Laval, 2725 Chemin Sainte-Foy, Sainte-Foy, Quebec, Canada.
Thorac Surg Clin. 2004 May;14(2):183-90. doi: 10.1016/S1547-4127(04)00012-X.
Lung cancer involving the carina can be treated by surgery, but patients must be carefully selected before the operation. Because pneumonectomy is required in addition to carinal resection, patients must be able to withstand the procedure, and they must be told that the operative mortality is 2 to 4 times higher than what is expected after standard pneumonectomy. Patients who have mediastinal nodal disease documented preoperatively by mediastinoscopy should not have this operation. In general, it is possible to perform a safe operation if the surgeon adheres to the principles of healthy bronchial suturing and restricts airway resection to a maximum distance of 4 cm. Surgeons must always remember, however, that it is better and safer to accept a positive resection margin than to have to deal with a bronchopleural fistula caused by anastomotic separation. Finally, reported long-term survival rates of 25% to 40% justify the use of this procedure.
累及隆突的肺癌可通过手术治疗,但术前必须仔细挑选患者。由于除隆突切除外还需要进行肺切除术,患者必须能够耐受该手术,并且必须告知他们手术死亡率比标准肺切除术后预期的高2至4倍。术前经纵隔镜检查证实有纵隔淋巴结疾病的患者不应进行此手术。一般来说,如果外科医生坚持健康支气管缝合原则并将气道切除限制在最大4厘米的距离,则可以进行安全的手术。然而,外科医生必须始终记住,接受阳性切缘比处理吻合口分离导致的支气管胸膜瘘更好、更安全。最后,报告的25%至40%的长期生存率证明了该手术的应用价值。