Rodriguez-Merchan E C, Rocino A, Ewenstein B, Bartha L, Batorova A, Goudemand J, Gringeri A, Joao-Diniz M, Lopaciuk S, Negrier C, Quintana M, Tagariello G, Tjonnfjord G E, Villar V A, Vorlova Z
Service of Traumatology and Orthopaedic Surgery, La Paz University Hospital, Madrid, Spain.
Haemophilia. 2004 Sep;10 Suppl 2:50-2. doi: 10.1111/j.1365-2516.2004.00941.x.
Summary. Participants in an international workshop on surgery in haemophilia patients with inhibitors developed a consensus summary of the findings and conclusions of the meeting. In the consensus, participants agreed upon revised definitions for minor and major surgery, including an intermediate degree of surgery. An evaluation system of intraoperative and postoperative bleeding was developed. Recommended doses of FEIBA((R)) and rFVIIa (both in bolus injections and in continuous infusion) for surgery were agreed. Participants also agreed on the main blood tests to be performed peri-operatively. They also suggested the need of a prospective evaluation in the future. Finally, the approximate number of surgical procedures and costs performed on haemophilia patients with inhibitors were analysed.
总结。血友病抑制物患者手术国际研讨会的参与者对会议的研究结果和结论形成了一份共识总结。在这份共识中，参与者就小手术和大手术的修订定义达成一致，其中包括中等程度的手术。制定了术中及术后出血的评估系统。就手术中FEIBA((R))和重组活化凝血因子VII（rFVIIa）的推荐剂量（包括单次推注和持续输注）达成一致。参与者还就围手术期应进行的主要血液检查达成一致。他们还建议未来需要进行前瞻性评估。最后，分析了血友病抑制物患者进行的外科手术的大致数量和费用。
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