保守性阴蒂保留手术治疗外阴鳞状细胞癌
Conservative clitoral preservation surgery in the treatment of vulvar squamous cell carcinoma.
作者信息
Chan John K, Sugiyama Valerie, Tajalli Tania R, Pham Huyen, Gu Mai, Rutgers Joanne, Monk Bradley J
机构信息
Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Stanford University School of Medicine, Stanford, CA 94305-5317, USA.
出版信息
Gynecol Oncol. 2004 Oct;95(1):152-6. doi: 10.1016/j.ygyno.2004.07.004.
OBJECTIVE
To determine the safety and efficacy of clitoral-sparing surgery in women with squamous cell carcinoma (SCCA) of the anterior vulva not involving the clitoris.
METHODS
Patients with vulvar SCCA diagnosed between 1984 and 2000 were identified and data collected. In this descriptive analysis, women treated with complete radical vulvectomy were compared to those treated with clitoral-sparing modified radical vulvectomy. All slides were re-reviewed.
RESULTS
Of the 41 women with vulvar carcinoma, 13 had clitoral-sparing modified vulvectomies (group A) while the remaining 28 underwent complete radical vulvectomies (group B). The 13 patients in group A included, 8 with stage I, 2 stage II, 2 stage III, and 1 with stage IV disease. The two groups had similar demographic and pathologic prognostic factors. After a median follow-up of 59 months, no patients in group A had loco-regional failure.
CONCLUSION
Clitoral-sparing vulvar cancer surgery does not compromise the rate of loco-regional control in patients and may be offered to selected women.
目的
确定保留阴蒂手术对外阴前部未累及阴蒂的鳞状细胞癌（SCCA）女性患者的安全性和有效性。
方法
确定1984年至2000年间诊断为外阴SCCA的患者并收集数据。在这项描述性分析中，将接受根治性外阴切除术的女性与接受保留阴蒂改良根治性外阴切除术的女性进行比较。所有切片均重新检查。
结果
41例外阴癌女性患者中，13例行保留阴蒂改良外阴切除术（A组），其余28例行根治性外阴切除术（B组）。A组的13例患者中，8例为I期，2例为II期，2例为III期，1例为IV期疾病。两组在人口统计学和病理预后因素方面相似。中位随访59个月后，A组无患者出现局部区域复发。
结论
保留阴蒂的外阴癌手术不会影响患者的局部区域控制率，可提供给选定的女性患者。
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