Bernier-Fébreau Christine, du Merle Laurence, Turlin Evelyne, Labas Valérie, Ordonez Juana, Gilles Anne-Marie, Le Bouguénec Chantal
Unité de Pathogénie Bactérienne des Muqueuses, Institut Pasteur, Paris, France.
Infect Immun. 2004 Oct;72(10):6151-6. doi: 10.1128/IAI.72.10.6151-6156.2004.
We showed that the deoK operon, which confers the ability to use deoxyribose as a carbon source, is more common among pathogenic than commensal Escherichia coli strains. The expression of the deoK operon increases the competitiveness of clinical isolates, suggesting that this biochemical characteristic plays a role in host infectivity.
我们发现,赋予利用脱氧核糖作为碳源能力的deoK操纵子在致病性大肠杆菌菌株中比共生大肠杆菌菌株中更为常见。deoK操纵子的表达增强了临床分离株的竞争力,这表明这种生化特性在宿主感染性中发挥作用。