Damase-Michel Christine, Vié Céline, Lacroix Isabelle, Lapeyre-Mestre Maryse, Montastruc J L
Department of Pharmacology, Research Unit of Pharmacoepidemiology, Faculté de Médecine, Toulouse, France.
Pharmacoepidemiol Drug Saf. 2004 Oct;13(10):711-5. doi: 10.1002/pds.954.
The aim of the present study was to determine whether community pharmacists recommend appropriate medications and give valid information to pregnant women.
A total of 163 community pharmacists randomly selected in the Midi-Pyrénées area were interviewed by means of an open questionnaire. Ten scenarios were proposed concerning back pain, headache, coughs and sore-throats, fever, constipation, nausea, dyspepsia, 'venous insufficiency', allergic rhinitis and insomnia.
Out of the total, 130 pharmacists accepted to answer. Out of them 94.5% reported advising homeopathy, especially for coughs and allergy. They often advised medication for pain, fever, nose and oropharynx disorders, 'venous insufficiency', dyspepsia or constipation. By contrast, they referred the women to the general practitioner for nausea and vomiting or back pain. Advice without drug dispensation was given for gastrointestinal disorders or 'venous insufficiency'. Phytotherapy only concerned 0.5-2% of the answers except for anxiety and sleep disturbances (59%), 'venous disorders'(17%) and sore-throat (9%). Pharmacists' answers were sometimes inappropriate involving (1) pharmacologically illogical advice, (2) drugs for which neither clinical nor experimental data are available and (3) drugs potentially harmful in pregnancy.
The present study shows that French community pharmacists do not always give appropriate advice to pregnant women. As primary health care providers, pharmacists have to improve counselling regarding drug use in pregnancy.
本研究旨在确定社区药剂师是否会为孕妇推荐合适的药物并提供有效信息。
通过开放式问卷对在南比利牛斯地区随机选取的163名社区药剂师进行了访谈。提出了10种情况,涉及背痛、头痛、咳嗽和喉咙痛、发烧、便秘、恶心、消化不良、“静脉功能不全”、过敏性鼻炎和失眠。
总共有130名药剂师接受回答。其中94.5%的人报告建议使用顺势疗法,尤其是针对咳嗽和过敏。他们经常建议使用治疗疼痛、发烧、鼻子和口咽疾病、“静脉功能不全”、消化不良或便秘的药物。相比之下,他们会让孕妇去看全科医生治疗恶心、呕吐或背痛。对于胃肠道疾病或“静脉功能不全”,会提供不涉及配药的建议。除焦虑和睡眠障碍(59%)、“静脉疾病”(17%)和喉咙痛(9%)外,植物疗法仅占回答的0.5 - 2%。药剂师的回答有时不合适,包括(1)药理学上不合逻辑的建议,(2)既无临床数据也无实验数据的药物,以及(3)对孕妇有潜在危害的药物。
本研究表明,法国社区药剂师并非总是能为孕妇提供合适的建议。作为初级医疗保健提供者,药剂师必须改进关于孕期用药的咨询服务。