氨基酸衍生的碘苯二甲酸酯：用于将烯烃氧化转化为氨基酸酯的试剂。

Amino acid-derived iodobenzene dicarboxylates: reagents for oxidative conversion of alkenes to amino acid esters.

作者信息

Koposov Alexey Y, Boyarskikh Vyacheslav V, Zhdankin Viktor V

机构信息

Department of Chemistry, University of Minnesota--Duluth, Duluth, Minnesota 55812, USA.

出版信息

Org Lett. 2004 Sep 30;6(20):3613-5. doi: 10.1021/ol0484714.

DOI:10.1021/ol0484714

PMID:15387561

Abstract

[reaction: see text] New amino acid-derived iodobenzene dicarboxylates were prepared by the reaction of (diacetoxyiodo)benzene with N-protected natural amino acids. These compounds in the presence of iodide anion can be used as reagents for beta-iodocarboxylation of alkenes leading to the respective amino acid esters.

摘要

[反应：见正文] 通过（二乙酰氧基碘）苯与N-保护的天然氨基酸反应制备了新型氨基酸衍生的碘苯二羧酸盐。这些化合物在碘离子存在下可用作烯烃β-碘羧化反应的试剂，生成相应的氨基酸酯。