Gonwa T A, Husberg B S, Klintmalm G B, Mai M L, Goldstein R M, Capehart J E, Miller A H, Johnston S B, Alivizatos P A
Transplantation Services, Baylor University Medical Center, Dallas, Tex. 75246.
J Heart Lung Transplant. 1992 Jan-Feb;11(1 Pt 1):152-5.
Three cases of combined heart and kidney transplantation are presented. All three patients suffered from end-stage kidney disease, one chronic glomerulonephritis, two diabetic nephropathy. Ages of the patients were 22, 30, and 39 years, respectively. Two of the patients had the diagnosis of dilated cardiomyopathy and the third had ischemic heart disease. Patient follow-up is from 6 to 30 months. None of the patients have had a heart rejection and only one has had a kidney rejection. Cardiac and renal function remain excellent in all three patients. Glomerular filtration rates range from 53 to 77 ml/min. These three cases are compared with other reported cases in the literature. Combined heart and kidney transplantation may be of benefit in selected persons.
本文报告了3例心脏和肾脏联合移植病例。所有3例患者均患有终末期肾病，其中1例为慢性肾小球肾炎，2例为糖尿病肾病。患者年龄分别为22岁、30岁和39岁。2例患者被诊断为扩张型心肌病，第3例患有缺血性心脏病。患者随访时间为6至30个月。所有患者均未发生心脏排斥反应，仅1例发生肾脏排斥反应。所有3例患者的心脏和肾功能均保持良好。肾小球滤过率在53至77 ml/分钟之间。将这3例病例与文献中其他报道的病例进行了比较。心脏和肾脏联合移植可能对特定人群有益。
