Ohta M, Nakahara K, Yasumitsu T, Ohsugi T, Maeda M, Kawashima Y
First Department of Surgery, Osaka University Medical School, Japan.
Chest. 1992 Mar;101(3):668-73. doi: 10.1378/chest.101.3.668.
To predict the postoperative improvement in performance status after bullectomy, preoperative pulmonary function and dyspneic grade were evaluated in 20 patients with giant bulla. The patients were divided into two groups, based on postoperative performance status: group 1 consisted of 15 patients with improved status after surgery; and group 2 of five patients with worsened status after temporary improvement. To determine correlation with the groups, preoperative functional measurements such as %VC, FEV1%, MMF, PEFR, RV/TLC, delta N2, LCI, and PNCD were then analyzed by the multivariate statistic method; results of delta N2 and FEV1% showed significant correlation with the groups. Prediction of the groups based on the two measurements agreed with the actual results except in one patient. These results show that postoperative improvement in performance status of patients with giant bulla can be predicted on the basis of preoperative pulmonary function.
为预测肺大疱切除术后患者功能状态的改善情况,对20例巨大肺大疱患者的术前肺功能和呼吸困难分级进行了评估。根据术后功能状态,将患者分为两组:第1组由15例术后状态改善的患者组成;第2组由5例术后短暂改善后状态恶化的患者组成。为确定与分组的相关性,随后采用多变量统计方法分析了术前功能指标,如肺活量百分比(%VC)、第一秒用力呼气容积百分比(FEV1%)、最大呼气中期流速(MMF)、呼气峰流速(PEFR)、残气量/肺总量(RV/TLC)、氮洗出率差值(delta N2)、肺一氧化碳弥散指数(LCI)和氮浓度差(PNCD);结果显示,氮洗出率差值和第一秒用力呼气容积百分比与分组具有显著相关性。基于这两项指标对分组的预测,除1例患者外,均与实际结果相符。这些结果表明,巨大肺大疱患者术后功能状态的改善可根据术前肺功能进行预测。