Holm S, Eriksson P, Karp K, Osterman G, Teien D
Department of Clinical Physiology, University Hospital, Umeå, Sweden.
J Intern Med. 1992 Feb;231(2):115-21. doi: 10.1111/j.1365-2796.1992.tb00511.x.
The width of the regurgitant jet at the aortic valve plane, i.e. the core flow diameter, the ratio of the jet width to the left ventricular outflow diameter, the regurgitant volume and regurgitant fraction were determined using two-dimensional, continuous wave and colour flow Doppler echocardiography. The relationship between the non-invasive measurements and semiquantitative angiographic grading of the regurgitant flow (1 + to 4+) was examined in a primary group of 20 patients with chronic aortic regurgitation. Cut-off points for the non-invasive measurements were selected so as to separate patients with mild or moderate regurgitation (1+ or 2+) from patients with moderately severe or severe regurgitation (3+ or 4+). These cut-off points were prospectively applied in a new group of 35 patients with aortic regurgitation to predict the angiographic grading. Jet width correctly predicted the angiographic grading in 86% of cases, the ratio of the jet width to the outflow diameter in 83% of cases, the regurgitant volume in 86% of cases and the regurgitant fraction in 91% of cases. We conclude that the severity of aortic regurgitation as determined by angiographic grading can be estimated with reasonable accuracy by non-invasive techniques based on colour flow imaging.
使用二维、连续波和彩色血流多普勒超声心动图测定主动脉瓣平面反流束的宽度，即核心血流直径、反流束宽度与左心室流出道直径的比值、反流量和反流分数。在20例慢性主动脉瓣反流的主要研究组患者中，检查了这些非侵入性测量值与反流半定量血管造影分级（1+至4+）之间的关系。选择非侵入性测量的截断点，以便将轻度或中度反流（1+或2+）患者与中重度或重度反流（3+或4+）患者区分开来。这些截断点被前瞻性地应用于35例主动脉瓣反流的新患者组，以预测血管造影分级。反流束宽度在86%的病例中正确预测了血管造影分级，反流束宽度与流出道直径的比值在83%的病例中、反流量在86%的病例中以及反流分数在91%的病例中正确预测了血管造影分级。我们得出结论，基于彩色血流成像的非侵入性技术可以合理准确地估计血管造影分级所确定的主动脉瓣反流严重程度。
