Green M H
Pennsylvania State University, Nutrition Department, University Park 16802.
J Nutr. 1992 Mar;122(3 Suppl):690-4. doi: 10.1093/jn/122.suppl_3.690.
A model is a representation of structure and a mathematical model describes mathematically the relationship between variables and/or parameters. Numerous types of mathematical models have been used to study biological systems that are of interest to nutritionists. This paper introduces some concepts that relate to the dynamic behavior of biological systems and discusses two modeling approaches that can be used in conjunction with kinetic studies. The two approaches, empirical compartmental modeling and model-based compartmental analysis, are subcategories of compartmental analysis. The objective of this brief introduction to modeling is to encourage more nutritionists to use compartmental analysis and other forms of mathematical modeling in their research.
模型是结构的一种表示形式,而数学模型则从数学角度描述变量和/或参数之间的关系。许多类型的数学模型已被用于研究营养学家感兴趣的生物系统。本文介绍了一些与生物系统动态行为相关的概念,并讨论了两种可与动力学研究结合使用的建模方法。这两种方法,即经验性隔室建模和基于模型的隔室分析,是隔室分析的子类别。对建模进行这一简要介绍的目的是鼓励更多营养学家在其研究中使用隔室分析和其他形式的数学建模。