Sato M, Kuwana N, Kojima Y, Tanaka N
Department of Neurosurgery, Yokohama Minami-Kyosai Hospital.
No Shinkei Geka. 1992 Feb;20(2):153-5.
As a low cephalic index (cephalic index = breadth x 100/length), also called "dolichocephaly" has often been observed in patients with chronic subdural hematomas, the relation between the occurrence of chronic subdural hematoma and the cephalic index was investigated. 62 patients (male: 51, female: 11) with chronic subdural hematomas who were admitted during the past 5 years, and 62 patients (male: 51, female: 11) aged 40 years and over who visited the hospital for head injury which caused no intracranial hematoma, randomly sampled, as a control group, a total of 124 patients were studied for cephalic index on plain craniogram. The average cephalic index was 79.0 for males and 81.3 for females in the chronic subdural hematoma group, compared with 82.1 for males and 83.3 for females in the control group. The former index was lower than the latter for both sexes. Dolichocephaly was observed in 8 out of 51 males (15.7%) with chronic subdural hematomas while it was observed in only 1 out of 51 males (2.0%) in the control group. Since it has been reported that dolichocephaly depends on the development of arcus superciliaris and protuberantia occipitalis externa by the interaction between androgen and GH in males as well as time of closure of the cranial suture in childhood, and as androgen accelerates offensive behavior and GH stimulates the synthesis of collagen, the occurrence of chronic subdural hematoma is potentially related with sexual or individual variation in such endocrinic environments.(ABSTRACT TRUNCATED AT 250 WORDS)
由于在慢性硬膜下血肿患者中经常观察到低头指数(头指数=宽度×100/长度),也称为“长头畸形”,因此对慢性硬膜下血肿的发生与头指数之间的关系进行了研究。研究对象为过去5年收治的62例慢性硬膜下血肿患者(男51例,女11例),以及随机抽取的62例40岁及以上因头部受伤就诊但未发生颅内血肿的患者作为对照组,共124例患者在头颅平片上测量头指数。慢性硬膜下血肿组男性平均头指数为79.0,女性为81.3;对照组男性为82.1,女性为83.3。两组中男女的头指数均以前者低于后者。51例慢性硬膜下血肿男性患者中有8例(15.7%)出现长头畸形,而对照组51例男性中只有1例(2.0%)出现。据报道,长头畸形取决于男性雄激素与生长激素的相互作用以及儿童期颅骨缝线闭合时间对眉弓和枕外隆突发育的影响,且雄激素促进攻击行为,生长激素刺激胶原蛋白合成,因此慢性硬膜下血肿的发生可能与这种内分泌环境中的性别或个体差异有关。(摘要截于250字)