SHELTON E K
Calif Med. 1950 Aug;73(2):173-7.
Hormonally active tumors of the adrenal cortex are either benign adenomas or adenocarcinomas. They may be located within the adrenal gland or as adrenal rests along the Wolffian tract. Hyperplastic cortical tissue without actual neoplastic formation is also capable of elaborating excessive cortical secretions.AT THE PRESENT STATE OF KNOWLEDGE, ANY ONE OR A COMBINATION OF THE FOLLOWING COMPOUNDS MAY BE ELABORATED IN A GIVEN CASE: the electrolytic, glucogenic, androgenic, or estrogenic corticosteroids. Whether or not Cushing's syndrome is primarily pituitary or adrenal in origin is still a matter of conjecture.
肾上腺皮质的激素活性肿瘤可为良性腺瘤或腺癌。它们可位于肾上腺内,也可作为肾上腺残余组织沿中肾管分布。没有实际肿瘤形成的增生性皮质组织也能够分泌过多的皮质分泌物。就目前的知识水平而言,在某一特定病例中,可能会分泌以下任何一种或几种化合物:电解质皮质激素、生糖皮质激素、雄激素或雌激素。库欣综合征的原发部位究竟是垂体还是肾上腺,目前仍存在争议。