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皮质类固醇在婴幼儿及儿童附件血管瘤治疗中的应用

Corticosteroids in the management of adnexal hemangiomas in infancy and childhood.

作者信息

Assaf A, Nasr A, Johnson T

机构信息

Department of Ophthalmology, College of Medicine, King Saud University, Riyadh, Saudi Arabia.

出版信息

Ann Ophthalmol. 1992 Jan;24(1):12-8.

PMID:1543320
Abstract

Adnexal hemangiomas are common in infancy and childhood. They can be interesting to the ophthalmologist for two reasons: cosmetic and functional (the second, the more important). By their natural history, they can produce serious visual consequences by producing refractive or stimulus-deprivation amblyopia. The management of adnexal hemangiomas is a challenge. The accepted method is most instances is corticosteroid therapy. This is administered either by local, intralesional, or systemic routes; the first is preferred. Steroid therapy can cause systemic and local side effects. Furthermore, a rebound effect can occur with this type of therapy. We present the cases of 12 patients with adnexal hemangiomas treated with steroids. These patients are reviewed, with emphasis on their responses and the complications of steroid therapy.

摘要

附件血管瘤在婴幼儿期很常见。它们引起眼科医生的兴趣有两个原因:一是美容方面,二是功能方面(后者更为重要)。从其自然病程来看,它们可通过导致屈光性或剥夺性弱视而产生严重的视觉后果。附件血管瘤的治疗颇具挑战性。在大多数情况下,公认的方法是皮质类固醇疗法。这种疗法可通过局部、瘤内或全身途径给药;首选局部给药。类固醇疗法可引起全身和局部副作用。此外,这种类型的疗法可能会出现反弹效应。我们报告了12例接受类固醇治疗的附件血管瘤患者的病例。对这些患者进行了回顾,重点关注他们的反应以及类固醇治疗的并发症。

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