Eckhardt Boris P, Hernandez Ramiro J
Department of Radiology, C. S. Mott Children's Hospital, 1500 E. Medical Center Drive, Ann Arbor, MI 48109-0252, USA.
Pediatr Radiol. 2004 Dec;34(12):943-7. doi: 10.1007/s00247-004-1261-1. Epub 2004 Sep 22.
To describe the usefulness of gradient-echo imaging and contrast-enhanced MR imaging in diagnosing and assessing the extent of pigmented villonodular synovitis (PVNS) in pediatric patients.
Retrospective analysis of five pediatric patients (median age 14 years) with PVNS of the knee examined with a 1.5-T unit. Signal characteristics were obtained comparing T1- and proton-density (PD)-weighted imaging with gradient-echo imaging and enhanced imaging. The extent of the disease was assessed using the arthroscopic approach. Signal intensity ratios were statistically analyzed.
Compared to PD- and T1-weighted imaging sequences, gradient-echo imaging provides superior depiction of the extent of the disease due to signal decay (T2*-effect) of hemosiderin-laden thickened synovium and masses. Inflamed synovium with low hemosiderin deposition was identified on enhanced imaging. Beside the suprapatellar bursa and Hoffa's fat pad, the area posterior to the cruciate ligaments is commonly involved. No bony abnormalities were present.
Gradient-echo imaging together with enhanced imaging is useful in diagnosing and assessing the extent of PVNS in pediatric patients. A low signal mass behind the cruciate ligaments may represent an important diagnostic feature. Bony abnormalities were always absent.
描述梯度回波成像和对比增强磁共振成像在诊断和评估小儿色素沉着绒毛结节性滑膜炎(PVNS)范围中的作用。
回顾性分析5例接受1.5-T设备检查的膝关节PVNS小儿患者(中位年龄14岁)。通过比较T1加权成像、质子密度(PD)加权成像与梯度回波成像及增强成像来获取信号特征。采用关节镜检查方法评估疾病范围。对信号强度比进行统计学分析。
与PD加权成像和T1加权成像序列相比,由于含铁血黄素沉着增厚的滑膜和肿块的信号衰减(T2*效应),梯度回波成像能更清晰地显示疾病范围。在增强成像上可识别出含铁血黄素沉积少的炎性滑膜。除髌上囊和 Hoffa 脂肪垫外,十字韧带后方区域也常受累。未发现骨质异常。
梯度回波成像联合增强成像有助于诊断和评估小儿PVNS的范围。十字韧带后方的低信号肿块可能是重要的诊断特征。骨质异常始终不存在。