Luo Deqing, Yu Le, Yang Limin, Zhu Qigan, Ren Hongyue, Liu Hui
Department of Orthopaedic Surgery, The Affiliated Southeast Hospital of Xiamen University, Orthopaedic Center of People's Liberation Army Zhangzhou 363000, Fujian Province, China.
Department of Pathology, The Affiliated Southeast Hospital of Xiamen University, Orthopaedic Center of People's Liberation Army Zhangzhou 363000, Fujian Province, China.
Int J Clin Exp Pathol. 2021 Mar 1;14(3):383-388. eCollection 2021.
Pigmented villonodular synovitis (PVNS) is a rare benign proliferative disorder of the synovium. It rarely occurs in adolescents, particularly in immature patients with bilateral manifestation.
We present a case of atypical and bilateral PVNS of wrist in a 14-year-old boy. Initially, the patient presented with left wrist pain and swelling without the history of trauma. Physical examination revealed an obvious lesion in the dorsal part of left wrist. Radiographs, computed tomography (CT) and magnetic resonance imaging (MRI) showed multiple abnormal signal shadows and arthroedema in the left wrist. Arthroscopy operation was performed, and histologic examination suggested the diagnosis of PVNS. Only 10 months later, the patient presented with the similar symptoms and signs in the right wrist. But MIR and histologic examination were atypical. In this article, we also review and summarize 26 studies on 30 adolescent patients with PVNS.
This study provides an example of atypical and bilateral PVNS in adolescents.
色素沉着绒毛结节性滑膜炎（PVNS）是一种罕见的滑膜良性增生性疾病。它很少发生于青少年，尤其是双侧发病的未成熟患者。
我们报告一例14岁男孩的非典型双侧腕关节PVNS病例。最初，患者出现左手腕疼痛和肿胀，无外伤史。体格检查发现左手腕背侧有明显病变。X线片、计算机断层扫描（CT）和磁共振成像（MRI）显示左手腕有多个异常信号影和关节水肿。进行了关节镜手术，组织学检查提示PVNS诊断。仅10个月后，患者右手腕出现类似症状和体征。但磁共振成像（MIR）和组织学检查不典型。在本文中，我们还回顾并总结了26项针对30例青少年PVNS患者的研究。
本研究提供了一例青少年非典型双侧PVNS病例。
