Cheras P A, Freemont A J, Sikorski J M
The University of Queensland Department of Surgery, Greenslopes Repatriation Hospital, Greenslopes, QLD 4120, Australia.
Osteoarthritis Cartilage. 1993 Oct;1(4):219-32. doi: 10.1016/s1063-4584(05)80328-0.
It has been proposed that nontraumatic ischemic necrosis of bone (INB) is a result of lipid associated intraosseous thrombosis. A histological study of 15 patients with INB confirmed the presence of intravascular lipid and thrombosis in the vessels of the femoral head. A similar analysis of 11 patients with primary osteoarthritis (OA) showed similar changes at lower levels. These changes were not observed in seven control femoral heads. The possibility that both INB and OA result from intraosseous thrombosis is discussed.
有人提出,非创伤性骨缺血性坏死(INB)是脂质相关的骨内血栓形成的结果。一项对15例INB患者的组织学研究证实,股骨头血管中存在血管内脂质和血栓形成。对11例原发性骨关节炎(OA)患者进行的类似分析显示,较低水平存在类似变化。在7个对照股骨头中未观察到这些变化。本文讨论了INB和OA均由骨内血栓形成引起的可能性。