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[英夫利昔单抗治疗后发生的致命性粟粒性肺结核]

[Fatal miliary tuberculosis following treatment with Infliximab].

作者信息

Karoui Sami, Bouallegue Lamia, Hamzaoui Samir, Filali Azza, Boubaker Jalel

机构信息

Service de Gastro-entérologie A, Hôpital la Rabta, Tunis.

出版信息

Tunis Med. 2004 Apr;82(4):393-6.

Abstract

We report the first Tunisian case of miliary tuberculosis in a patient who received Infliximab for Crohn's disease with uretrorectal and ano-perineal fistula developed 4 weeks after the start of treatment. We suggest that diagnosis of latent tuberculosis infection is important before treatment with Infliximab is initiated and that antituberculous medication must be prescribed immediately in case of occurrence of unexplained fever after treatment with Infliximab.

摘要

我们报告了突尼斯首例粟粒性肺结核病例,该患者因克罗恩病伴直肠尿道及肛门会阴瘘接受英夫利昔单抗治疗,在治疗开始4周后发病。我们建议在开始使用英夫利昔单抗治疗前,对潜伏性结核感染进行诊断很重要,并且在英夫利昔单抗治疗后出现不明原因发热时,必须立即开具抗结核药物。

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