Kalra Mannudeep K, Maher Michael M, Kamath Ravi S, Horiuchi Tetsuya, Toth Thomas L, Halpern Elkan F, Saini Sanjay
Department of Radiology, Division of Abdominal Imaging and Intervention, Massachusetts General Hospital and Harvard Medical School, White 270-E, 55 Fruit St, Boston, MA 02114, USA.
Radiology. 2004 Oct;233(1):241-9. doi: 10.1148/radiol.2331031505.
To retrospectively determine the optimal noise indexes required to obtain diagnostically acceptable computed tomographic (CT) images of the abdomen and pelvis with z-axis modulation.
Ninety-five patients underwent 16-section multi-detector row CT of the abdomen and pelvis with z-axis modulation at noise indexes of 10.5, 11.0, 11.5, and 12.0 HU with 10-380 mA. Subsequently, 58 patients were scanned at noise indexes of 12.5 and 15.0 HU with 75-380 mA. The weights of all subjects were recorded, and transverse and anteroposterior diameters were measured. The CT images were evaluated for abnormalities and graded for image quality in terms of noise and diagnostic acceptability by using a five-point scale. Objective noise in the liver parenchyma was measured, and the tube current was recorded at each section in all 153 patients. Statistical analyses were performed to determine the appropriate noise index and to assess the effect of patient weight and abdominal diameters on image noise and diagnostic acceptability at different noise indexes. Tube current-time products (in milliampere seconds) at various noise indexes were compared with those at CT previously performed without z-axis modulation.
No significant difference in subjective image noise or diagnostic acceptability was found at noise indexes of 10.5-15.0 HU (P =.14), and objective noise was significantly inferior only at a noise index of 15.0 HU (P =.009). Compared with CT scanning at a 10.5-HU noise index, CT scanning at 12.5- and 15.0-HU noise indexes yielded, respectively, 10.0% and 41.3% reductions in radiation exposure. Patient weight and abdominal diameters affected subjective image quality.
Use of a 15.0-HU noise index at 75-380 mA results in acceptable subjective image noise and diagnostic acceptability but significantly greater objective image noise at routine abdominal-pelvic CT. For greater image quality demands, a noise index of 12.5 HU results in acceptable image quality and a 19.6% reduction in radiation exposure.
回顾性确定在进行腹部和骨盆的z轴调制计算机断层扫描(CT)时,获得诊断可接受图像所需的最佳噪声指数。
95例患者接受了16排多层螺旋CT腹部和骨盆扫描,扫描时采用z轴调制,噪声指数分别为10.5、11.0、11.5和12.0 HU,管电流为10 - 380 mA。随后,58例患者以75 - 380 mA的管电流进行扫描,噪声指数分别为12.5和15.0 HU。记录所有受试者的体重,并测量其横径和前后径。对CT图像进行异常评估,并根据噪声和诊断可接受性使用五点量表对图像质量进行分级。测量肝实质的客观噪声,并记录153例患者每一层的管电流。进行统计分析以确定合适的噪声指数,并评估患者体重和腹部直径对不同噪声指数下图像噪声和诊断可接受性的影响。将不同噪声指数下的管电流 - 时间乘积(毫安秒)与之前未进行z轴调制的CT扫描时的管电流 - 时间乘积进行比较。
在噪声指数为10.5 - 15.0 HU时,主观图像噪声或诊断可接受性无显著差异(P = 0.14),仅在噪声指数为15.0 HU时客观噪声显著较差(P = 0.009)。与噪声指数为10.5 HU的CT扫描相比,噪声指数为12.5和15.0 HU的CT扫描辐射暴露分别降低了10.0%和41.3%。患者体重和腹部直径影响主观图像质量。
在常规腹部 - 骨盆CT中,使用75 - 380 mA的15.0 HU噪声指数可获得可接受的主观图像噪声和诊断可接受性,但客观图像噪声显著更高。对于更高的图像质量要求,12.5 HU噪声指数可获得可接受的图像质量,且辐射暴露降低19.6%。