Kageshima K, Wakasugi B, Shiotani M, Ooseto K, Yuda Y, Karasawa H, Ohno K
Department of Anesthesiology, Jikei University School of Medicine, Tokyo.
Masui. 1992 Jan;41(1):106-10.
Of 2,667 patients with herpes zoster who visited our hospital between January 1972 and March 1989, 136 patients whose treatments were started after more than 6 months following the onset were subjects of the present study. Thus we performed a retrospective study of the therapeutic effects of sympathetic ganglion block (using alcohol) on postherpetic neuralgia left untreated for more than 6 months after the onset. After more than 1 year following the onset, the disease was nearly or completely cured in 9 of 37 patients (24%) treated with sympathetic ganglion block with alcohol and in 6 of 34 (17.6%) without the treatment. Thus the patients who underwent sympathetic ganglion block with alcohol tended to show better results. The above findings suggest that, in patients with postherpetic neuralgia in whom the initiation of treatment was delayed, treatment mainly consisting of thoracic or lumbar sympathetic ganglion block using alcohol in combination with antidepressants and antianxiety drugs can greatly improve patients' activities of daily life and that, at present, this method is most effective in relieving postherpetic neuralgia.
在1972年1月至1989年3月期间到我院就诊的2667例带状疱疹患者中，本研究选取了136例在发病6个月后才开始治疗的患者。因此，我们对交感神经节阻滞（使用酒精）对发病6个月后未治疗的带状疱疹后神经痛的治疗效果进行了回顾性研究。发病1年多后，37例接受酒精交感神经节阻滞治疗的患者中有9例（24%）疾病几乎或完全治愈，34例未接受治疗的患者中有6例（17.6%）治愈。因此，接受酒精交感神经节阻滞治疗的患者往往效果更好。上述研究结果表明，对于治疗延迟的带状疱疹后神经痛患者，以酒精胸段或腰段交感神经节阻滞为主，联合使用抗抑郁药和抗焦虑药，可显著改善患者的日常生活活动能力，且目前该方法在缓解带状疱疹后神经痛方面最为有效。
