Ali N M
Department of Anesthesiology, University of New Mexico School of Medicine, Albuquerque 87131, USA.
Reg Anesth. 1995 May-Jun;20(3):227-33.
To examine specifically the role of sympathetic block in the prevention of postherpetic neuralgia by its application in the treatment of acute herpes zoster.
Data sources included a Medline search and cross-referencing of articles and text books. A total of 84 references were reviewed. Peer-reviewed articles were selected according to their relevance to the subject and originality. The data were critically analyzed by the author with the specific intention of avoiding bias.
The opinion of the medical community is divided on the role of sympathetic block in preventing postherpetic neuralgia because of the lack of controlled trials and the conflicting retrospective reports as to its effectiveness. While many reports promote the early use of sympathetic blocks during acute herpes zoster to prevent postherpetic neuralgia, others deny their value.
Considering the degree of uncertainty, and the seriousness of postherpetic neuralgia, sympathetic block in addition to treatment with acyclovir should be considered early during acute herpes zoster. Large controlled trials are needed to provide the necessary scientific evidence.
通过将交感神经阻滞应用于急性带状疱疹的治疗，具体研究其在预防带状疱疹后神经痛中的作用。
数据来源包括医学文献数据库检索以及对文章和教科书的交叉引用。共查阅了84篇参考文献。根据与主题的相关性和原创性筛选同行评审文章。作者对数据进行严格分析，特别旨在避免偏差。
由于缺乏对照试验以及关于其有效性的回顾性报告相互矛盾，医学界对于交感神经阻滞在预防带状疱疹后神经痛中的作用存在分歧。虽然许多报告提倡在急性带状疱疹期间早期使用交感神经阻滞来预防带状疱疹后神经痛，但其他报告则否认其价值。
考虑到不确定性的程度以及带状疱疹后神经痛的严重性，在急性带状疱疹早期除使用阿昔洛韦治疗外，还应考虑交感神经阻滞。需要进行大规模对照试验以提供必要的科学证据。
