Grossi E A, Galloway A C, Parish M A, Asai T, Gindea A J, Harty S, Kronzon I, Spencer F C, Colvin S B
Department of Surgery, New York University Medical Center, N.Y. 10016.
J Thorac Cardiovasc Surg. 1992 Mar;103(3):466-70.
Systolic anterior motion of the mitral valve with left ventricular outflow tract obstruction after Carpentier-type mitral reconstruction with ring annuloplasty has led some surgeons to abandon an otherwise successful repair or to avoid use of a rigid ring. To assess the long-term significance of such motion, we studied 439 patients undergoing Carpenter mitral reconstruction at our institution between March 1981 and June 1990. The hospital mortality rate was 4.8% (21/439) overall and 3.7% (9/243) for isolated mitral reconstruction. Systolic anterior motion was found in 6.4% (28/438) after the operation, and 2.3% (10/438) had a coexisting left ventricular outflow tract gradient (mean 53 mm Hg). Of the 28 patients with systolic anterior motion, 27 (96.4%) had leaflet prolapse, 17 (60.7%) had undergone more than a 3 cm resection of the posterior leaflet, and two (7.1%) had preexisting idiopathic hypertrophic subaortic stenosis. All patients were treated medically, 14 with negative inotropic agents. Follow-up echocardiograms at a mean of 32 months demonstrated the disappearance of systolic anterior motion in 13 of 28 patients (46.4%) and resolution of the outflow tract gradient in 10 of 10 (100%). At follow-up only one patient was in New York Heart Association class III or IV and required reoperation for rheumatic mitral insufficiency. These data demonstrate that systolic anterior motion after Carpentier mitral reconstruction with ring annuloplasty is not prevalent and should be managed medically in most cases. Associated left ventricular outflow tract obstruction resolves with medical treatment.
采用人工瓣环行Carpentier式二尖瓣重建术后出现二尖瓣收缩期前向运动并伴有左心室流出道梗阻,这使得一些外科医生放弃原本成功的修复手术,或避免使用硬质人工瓣环。为评估这种运动的长期影响,我们研究了1981年3月至1990年6月间在我院接受Carpentier二尖瓣重建术的439例患者。总体医院死亡率为4.8%(21/439),单纯二尖瓣重建术的死亡率为3.7%(9/243)。术后发现6.4%(28/438)的患者出现收缩期前向运动,2.3%(10/438)的患者同时存在左心室流出道压差(平均53mmHg)。在28例出现收缩期前向运动的患者中,27例(96.4%)存在瓣叶脱垂,17例(60.7%)后叶切除超过3cm,2例(7.1%)术前存在特发性肥厚性主动脉瓣下狭窄。所有患者均接受药物治疗,其中14例使用负性肌力药物。平均32个月的随访超声心动图显示,28例患者中有13例(46.4%)收缩期前向运动消失,10例(100%)流出道压差消失。随访时,只有1例患者处于纽约心脏协会III或IV级,因风湿性二尖瓣关闭不全需要再次手术。这些数据表明,采用人工瓣环行Carpentier二尖瓣重建术后的收缩期前向运动并不常见,大多数情况下应采用药物治疗。相关的左心室流出道梗阻通过药物治疗可得到缓解。