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导致二尖瓣修复失败的流出道梗阻机制。瓣叶对合的前向移位。

Mechanism of outflow tract obstruction causing failed mitral valve repair. Anterior displacement of leaflet coaptation.

作者信息

Lee K S, Stewart W J, Lever H M, Underwood P L, Cosgrove D M

机构信息

Department of Cardiology, Cleveland Clinic Foundation, OH 44195.

出版信息

Circulation. 1993 Nov;88(5 Pt 2):II24-9.

PMID:8222161
Abstract

BACKGROUND

Systolic anterior motion of the mitral valve causing left ventricular outflow tract obstruction occurs in 1% to 2% of patients having mitral valve repair, in some cases requiring further surgery to relieve the obstruction, but the mechanism and the geometry involved are not certain.

METHODS AND RESULTS

We studied 14 patients who developed systolic anterior motion and left ventricular outflow tract obstruction, all after posterior leaflet resection and annuloplasty, in whom a second repair eliminated systolic anterior motion by complete (n = 6) or partial (n = 8) ring removal. Intraoperative transesophageal echocardiography was recorded before pump, after failed repair during left ventricular outflow tract obstruction, and after a corrective second pump run to relieve the systolic anterior motion. Systolic anterior motion occurred when the mitral valve coaptation to septum distance was reduced (before, 26.5 +/- 4.3; during systolic anterior motion, 17.4 +/- 4.4 versus after second pump, 23.4 +/- 6.9 mm) and the mitral valve coaptation to posterior mitral annulus distance was greater (before, 18.9 +/- 3.4; during systolic anterior motion, 22.2 +/- 4.6 versus after second pump, 17.4 +/- 3.6 mm), both P < .01. Comparing dimensions before pump, during systolic anterior motion, and after the second pump, there were no differences in left ventricular cavity diameter in systole or diastole, the septum to posterior annulus distance, or the angle between the aortic and mitral annular planes.

CONCLUSIONS

After mitral repair, left ventricular outflow tract obstruction occurs when the mitral coaptation line is displaced anteriorly. When systolic anterior motion occurs, reduction of the amount of annuloplasty or use of the posterior leaflet sliding procedure may eliminate this problem. Understanding the geometry of this phenomenon may facilitate preoperative echo selection of high-risk patients (those with large redundant posterior leaflets and relatively normal ventricular size) and modification of surgical technique to avoid the problem of outflow tract obstruction after mitral valve repair.

摘要

背景

二尖瓣收缩期前向运动导致左心室流出道梗阻发生于1%至2%接受二尖瓣修复的患者中,某些情况下需要进一步手术以解除梗阻,但其机制及相关几何学特征尚不确定。

方法与结果

我们研究了14例出现收缩期前向运动及左心室流出道梗阻的患者,均在二尖瓣后叶切除及瓣环成形术后,其中二次修复通过完全(n = 6)或部分(n = 8)移除瓣环消除了收缩期前向运动。术中经食管超声心动图记录于体外循环前、左心室流出道梗阻时初次修复失败后以及纠正性二次体外循环运行以解除收缩期前向运动后。当二尖瓣与室间隔贴合距离缩短(体外循环前,26.5±4.3;收缩期前向运动时,17.4±4.4对比二次体外循环后,23.4±6.9mm)且二尖瓣与二尖瓣后瓣环贴合距离增大(体外循环前,18.9±3.4;收缩期前向运动时,22.2±4.6对比二次体外循环后,17.4±3.6mm)时出现收缩期前向运动,两者P均<0.01。比较体外循环前、收缩期前向运动时及二次体外循环后各维度,收缩期或舒张期左心室腔直径、室间隔至后瓣环距离或主动脉与二尖瓣瓣环平面夹角均无差异。

结论

二尖瓣修复后,当二尖瓣贴合线向前移位时会发生左心室流出道梗阻。当出现收缩期前向运动时,减少瓣环成形量或采用后叶滑动术可能消除此问题。了解这一现象的几何学特征可能有助于术前超声心动图筛选高危患者(具有大的多余后叶且心室大小相对正常者)并改进手术技术以避免二尖瓣修复后出现流出道梗阻问题。

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