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在喀布尔对阿富汗儿童进行的结核菌素皮肤试验调查。

A tuberculin skin test survey among Afghan children in Kabul.

作者信息

Dubuis M, Fiekert K, Johnston M, Neuenschwander B E, Rieder H L

机构信息

Medair, Ecublens, Switzerland.

出版信息

Int J Tuberc Lung Dis. 2004 Sep;8(9):1065-72.

Abstract

SETTING

Kabul, Afghanistan, October to November 2000.

OBJECTIVE

To determine the prevalence and the average annual risk of infection with Mycobacterium tuberculosis (ARTI).

METHODS

A cluster sampling method was selected to carry out the survey. Sub-divisions of Kabul's districts were chosen, and door-to-door visits were carried out to register the children. The prevalence of tuberculous infection was determined using a cut-off point to denote infection and mixture analysis. The average ARTI was derived algebraically from the prevalence estimates.

RESULTS

The tuberculin skin test was administered and read in 89% of registered children. Utilising a cut-off point of > or = 8 mm in duration, the estimated prevalence of tuberculous infection was 4.3% and the calculated average ARTI was 0.61%. Using mixture analysis, the average ARTI was estimated to be 0.34% (95% credibility interval 0.23-0.54). This indicates a substantial decrease from the estimated ARTI of 2.55% calculated in the 1963 survey.

CONCLUSIONS

There has been a large decrease in the risk of tuberculous infection in Kabul since the last assessment. The adverse situation in the past decades does not appear to have severely affected the epidemiological situation.

摘要

背景

2000年10月至11月,阿富汗喀布尔。

目的

确定结核分枝杆菌感染的患病率和平均年感染风险(ARTI)。

方法

采用整群抽样方法进行调查。选取喀布尔各区的分区,挨家挨户走访以登记儿童。使用一个分界点来表示感染,并通过混合分析确定结核感染的患病率。平均ARTI通过患病率估计值代数得出。

结果

对89%的登记儿童进行了结核菌素皮肤试验并读取结果。使用持续时间≥8毫米的分界点,结核感染的估计患病率为4.3%,计算得出的平均ARTI为0.61%。通过混合分析,平均ARTI估计为0.34%(95%可信区间0.23 - 0.54)。这表明与1963年调查计算得出的估计ARTI 2.55%相比有大幅下降。

结论

自上次评估以来,喀布尔结核感染风险大幅下降。过去几十年的不利情况似乎并未严重影响流行病学状况。

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