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The effect of germfree and SPF maintenance conditions on the lifespan and diseases of small laboratory animals.

作者信息

Deerberg F, Pittermann W

出版信息

J S Afr Vet Assoc. 1978 Sep;49(3):179-82.

PMID:154573
Abstract

The mortality rates and spontaneous diseases defining the course of natural mortality graphs in colonies of Han: NMRI mice kept under conventional, SPF and germfree maintenance conditions are reported. A specific problem in SPF colonies is caused by ubiquitous germs. The lesions and possible reasons for such types of infections are discussed.

摘要

相似文献

1
The effect of germfree and SPF maintenance conditions on the lifespan and diseases of small laboratory animals.
J S Afr Vet Assoc. 1978 Sep;49(3):179-82.
2
Twelve years experience in establishing larger colonies of small laboratory animals under SPF conditions by means of germfree technology.拥有十二年通过无菌技术在无特定病原体（SPF）条件下建立大型小型实验动物群落的经验。
J S Afr Vet Assoc. 1978 Sep;49(3):175-7.
3
[Spontaneous diseases and pathologic changes in Han: NMRI nu/nu mice].[Han: NMRI 裸鼠的自发性疾病及病理变化]
Z Versuchstierkd. 1980;22(5-6):309-16.
4
Operating procedures, equipment and housing facilities to maintain small laboratory animals under SPF conditions in large breeding colonies and in experiments.
J S Afr Vet Assoc. 1978 Sep;49(3):171-4.
5
Higher resistance of germfree mice to dianhydrodulcitol, a lymphotropic cytostatic agent.无菌小鼠对亲淋巴细胞性细胞生长抑制剂二去水卫矛醇具有更高的抵抗力。
Acta Microbiol Acad Sci Hung. 1982;29(1):33-40.
6
The breeding and use of specific pathogen-free (SPF) rats.无特定病原体（SPF）大鼠的繁育与使用。
J S Afr Vet Assoc. 1978 Sep;49(3):183.
7
[Comparative studies on the occurrence of spontaneous diseases and spontaneous deaths in conventional and specific germ-free female NMRI-HAN mice].
Z Versuchstierkd. 1970;12(6):341-7.
8
Immunological responses in germfree mice infected with murine cytomegalovirus.
Tokai J Exp Clin Med. 1990 Mar;15(1):13-20.
9
[Mice and rats (1)].
Jikken Dobutsu. 1974 Apr;23(2):93-5.
10
Anti-mu induces lymphoma in germfree congenitally athymic (nude) but not in heterozygous (nu/+) mice.抗μ链抗体可在无菌先天性无胸腺（裸）小鼠中诱发淋巴瘤，但在杂合子（nu/+）小鼠中则不会。
J Immunol. 1983 Oct;131(4):2069-73.

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Oncogenic activity of the BK type of human papova virus in newborn Wistar rats.BK型人乳头多瘤病毒在新生Wistar大鼠中的致癌活性。
Arch Virol. 1981;69(3-4):239-51. doi: 10.1007/BF01317339.