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古典猪瘟病毒“C”株。口服疫苗接种后多长时间可检测到?

Classical swine fever virus Strain 'C'. How long is it detectable after oral vaccination?

作者信息

Kaden V, Lange E, Riebe R, Lange B

机构信息

Institute of Infectology, Federal Research, Centre for Virus Diseases of Animals, Friedrich-Loeffler-Institutes, Boddenblick 5a, 17493 Greifswald-Insel Riems, Germany.

出版信息

J Vet Med B Infect Dis Vet Public Health. 2004 Aug;51(6):260-2. doi: 10.1111/j.1439-0450.2004.00766.x.

Abstract

To determine the persistence period of C-strain vaccine virus in immunized animals, domestic pigs and wild boars were vaccinated orally and killed on different days post vaccinationem (dpv). Tissue samples were taken at necropsy from both species for detection of C-strain virus. From domestic pigs nasal swabs and faeces were also collected. During the investigation period (2-12 dpv) vaccine virus could never be detected in nasal secretions and in faeces of vaccinated domestic pigs. In contrast, C-strain virus was found in organs until day 8 pv in domestic pigs and until day 9 pv in wild boars. Whereas in domestic pigs virus was detected in tonsils, Ln. mandibularis or in spleen, in wild boar it only was found in tonsils. We conclude that C-strain vaccine virus is not detectable in wild boars longer than 10-12 days after intake of the vaccine baits.

摘要

为确定C株疫苗病毒在免疫动物体内的持续时间,对家猪和野猪进行口服疫苗接种,并在接种后不同天数(dpv)处死。在尸检时从这两个物种采集组织样本以检测C株病毒。对于家猪,还采集了鼻拭子和粪便样本。在调查期间(接种后2 - 12天),从未在接种家猪的鼻分泌物和粪便中检测到疫苗病毒。相比之下,在家猪中直到接种后第8天、在野猪中直到接种后第9天,在器官中都发现了C株病毒。家猪的病毒在扁桃体、下颌淋巴结或脾脏中被检测到,而野猪仅在扁桃体中发现病毒。我们得出结论,在摄入疫苗诱饵后10 - 12天以上,在野猪中无法检测到C株疫苗病毒。

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