Eckstein A, Schulz S, Esser J
Zentrum für Augenheilkunde, Universität Essen.
Klin Monbl Augenheilkd. 2004 Sep;221(9):769-75. doi: 10.1055/s-2004-813594.
In Graves' ophthalmopathy squint can be corrected in about two-thirds of the patients with a single recession of an inferior or medialis rectus muscle. The dose-effect correlation is linear over a wide range. Combined vertical and convergent misalignments are rare. The aim of this study was to evaluate the dose-effects in combined recessions of medialis and inferior rectus muscles.
The dose-effect of combined recessions (one side medialis and inferior n = 28, both sides medialis and one side inferior n = 9) was evaluated. The control groups were patients with Graves' ophthalmopathy, who had single inferior recession (n = 187), single medialis recession (n = 37) and bilateral medialis recession (n = 44).
Small hypotropias (up to 5 degrees ) at the eye with the poorer abduction disappear after single (17 of 21) or bilateral (11 of 19) medialis recessions. This obvious influence of horizontal recession on the vertical angle leads to a higher dose-effect for the inferior recessions in combined surgery, and was stronger for bilateral cases (from 2.0 degrees to 2.7 degrees /mm recession) than for unilateral cases (from 2.0 degrees to 2.2 degrees /mm recession). The dose-effect for medialis recession in combined surgery increased for the unilateral procedures only from 1.7 degrees to 1.8 degrees /mm recession and not for the bilateral medialis recession.
The dose-effect for combined medialis and inferior recessions is enhanced and varies to a much higher degree in comparison to single muscle recessions. Because of the higher variability, patients who need both medialis and inferior recession should be better operated in separate sessions, beginning with the horizontal muscle(s).
在格雷夫斯眼病中,约三分之二的患者通过单一下直肌或内直肌后徙术可矫正斜视。在很宽的范围内,剂量 - 效应呈线性关系。垂直和集合性斜视合并存在的情况很少见。本研究的目的是评估内直肌和下直肌联合后徙术的剂量 - 效应。
评估联合后徙术(一侧内直肌和下直肌,n = 28;双侧内直肌和一侧下直肌,n = 9)的剂量 - 效应。对照组为格雷夫斯眼病患者,分别接受单一下直肌后徙术(n = 187)、单一内直肌后徙术(n = 37)和双侧内直肌后徙术(n = 44)。
外展较差眼出现的小度数下斜视(达5度)在单次(21例中的17例)或双侧(19例中的11例)内直肌后徙术后消失。水平后徙术对垂直角度的这种明显影响导致联合手术中下直肌后徙术的剂量 - 效应更高,双侧病例(从2.0度/毫米后徙增加到2.7度/毫米后徙)比单侧病例(从2.0度/毫米后徙增加到2.2度/毫米后徙)更明显。联合手术中内直肌后徙术的剂量 - 效应仅在单侧手术时从1.7度/毫米后徙增加到1.8度/毫米后徙,双侧内直肌后徙术则无变化。
与单一肌肉后徙术相比,内直肌和下直肌联合后徙术的剂量 - 效应增强且变化程度更高。由于变异性更高,需要同时进行内直肌和下直肌后徙术的患者最好分阶段手术,先处理水平肌。