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格雷夫斯眼眶病患者的单侧和双侧内直肌后徙术

Unilateral and bilateral medial rectus recession in Graves' Orbitopathy patients.

作者信息

Jellema Hinke Marijke, Saeed Peerooz, Braaksma-Besselink Yvette, Schuit Anneroos, Kloos Roel, Mourits Maarten P

机构信息

Department of Ophthalmology, University of Amsterdam , the Netherlands and.

出版信息

Strabismus. 2014 Dec;22(4):182-7. doi: 10.3109/09273972.2014.962749. Epub 2014 Oct 13.

DOI:10.3109/09273972.2014.962749
PMID:25310344
Abstract

PURPOSE

To evaluate the effect of uni- and bilateral medial rectus recession on squint angle and ductions in Graves' Orbitopathy (GO) patients.

DESIGN

Retrospective case series.

MATERIALS AND METHODS

Consecutive GO patients seen between January 2000 and March 2012 who were operated on one or both medial rectus muscles were selected for the study. Data regarding squint angle, abduction, and adduction were collected starting 3 months before surgery and 3 and 6-12 months after surgery.

RESULTS

102 patients were eligible for inclusion. Of these, 24 patients were operated on one medial rectus and 78 on two medial rectus muscles. The dose-effect response was 1.0 [-0.6-3.8]°/mm in the unilateral and 1.4 [0.2-3.0]°/mm in the bilateral group (p=0.000). In the bilateral group, the maximal abduction and adduction changed significantly (p=0.000). However, the total duction range remained unchanged (unilateral: p=0.525; bilateral: p=0.137). The extent of the preoperative abduction did not influence the dose-effect response (r=-0.234; p=0.040), nor did the muscle volume (unilateral p=0.989; bilateral p=0.397). Twenty-three patients (23%) needed additional horizontal squint surgery.

CONCLUSION

In this large series of medial rectus recessions in patients with Graves' disease we found significantly lower dose-effect response ratios as compared to other studies. The amount of abduction deficit does not influence outcome.

摘要

目的

评估单侧和双侧内直肌后徙术对格雷夫斯眼眶病(GO)患者斜视角度和眼球运动的影响。

设计

回顾性病例系列研究。

材料与方法

选取2000年1月至2012年3月期间接受单侧或双侧内直肌手术的连续性GO患者进行研究。收集术前3个月以及术后3个月和6 - 12个月的斜视角度、外展和内收数据。

结果

102例患者符合纳入标准。其中,24例行单侧内直肌手术,78例行双侧内直肌手术。单侧组的剂量 - 效应反应为1.0[-0.6 - 3.8]°/mm,双侧组为1.4[0.2 - 3.0]°/mm(p = 0.000)。在双侧组中,最大外展和内收有显著变化(p = 0.000)。然而,总的眼球运动范围保持不变(单侧:p = 0.525;双侧:p = 0.137)。术前外展程度不影响剂量 - 效应反应(r = -0.234;p = 0.040),肌肉体积也不影响(单侧p = 0.989;双侧p = 0.397)。23例患者(23%)需要额外的水平斜视手术。

结论

在这一大组格雷夫斯病患者的内直肌后徙术中,我们发现与其他研究相比,剂量 - 效应反应率显著更低。外展不足的程度不影响手术结果。

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