Tysler M, Turzová M, Szathmáry V
Institute of Measurement Science SAS, Dubravská cesta 9, 842 19 Bratislava, Slovakia.
Stud Health Technol Inform. 2002;90:35-40.
Possibility to obtain information about local changes of heart repolarization from body surface potentials was studied on a model. Activation-recovery intervals (ARI) in surface ECG leads were tested as indicators of changed repolarization in the underlying myocardium. ECG signals corresponding to activation of myocardium with normal and changed action potential duration were simulated on the surface of a realistic inhomogeneous torso. ARI intervals were derived from all ECG signals and displayed as surface ARI maps. Results suggest that shortening and prolongation of action potentials in anterior myocardial regions can be visible in corresponding areas on surface ARI maps while only prolongation in postero-lateral regions can be observed. Reproducibility of ARI maps was checked on real measurements using 63 and 192 surface ECG leads. Obtained ARI maps exhibited acceptable reproducibility with correlation of 0.73 to 0.87. Based on the model and experimental results it is hoped that ARI maps can give some insight into the myocardium repolarization and help to recognize tissue with changed properties, primarily in heart regions underlying the anterior chest.
在一个模型上研究了从体表电位获取心脏复极化局部变化信息的可能性。测试了体表心电图导联中的激活-恢复间期（ARI）作为潜在心肌复极化变化的指标。在逼真的非均匀躯干表面模拟了与正常和改变动作电位持续时间的心肌激活相对应的心电图信号。从所有心电图信号中导出ARI间期并显示为表面ARI图。结果表明，前壁心肌区域动作电位的缩短和延长在表面ARI图的相应区域可见，而后外侧区域仅观察到延长。使用63和192个体表心电图导联对实际测量的ARI图的可重复性进行了检查。获得的ARI图显示出可接受的可重复性，相关性为0.73至0.87。基于该模型和实验结果，希望ARI图能够对心肌复极化提供一些见解，并有助于识别性质改变的组织，主要是前胸下方的心脏区域。
