Culleton Bruce F, Hemmelgarn Brenda
Semin Dial. 2004 Sep-Oct;17(5):342-5. doi: 10.1111/j.0894-0959.2004.17360.x.
Cardiovascular disease (CVD) is the leading cause of morbidity and mortality in patients with end-stage renal disease (ESRD). Despite its significant impact on health outcomes, which would imply a need for aggressive intervention, both CVD and CVD risk factors are inadequately treated in this patient population. The reasons for this inadequate treatment are unclear. This article reviews the contribution of traditional risk factors to the burden of CVD in ESRD patients, outlines the evidence regarding undertreatment of CVD and traditional CVD risk factors, and identifies potential factors that may be responsible for inadequate cardiovascular care in ESRD patients.
心血管疾病(CVD)是终末期肾病(ESRD)患者发病和死亡的主要原因。尽管其对健康结局有重大影响,这意味着需要积极干预,但在这一患者群体中,CVD及其危险因素的治疗均不充分。这种治疗不充分的原因尚不清楚。本文回顾了传统危险因素对ESRD患者CVD负担的影响,概述了关于CVD及传统CVD危险因素治疗不足的证据,并确定了可能导致ESRD患者心血管护理不充分的潜在因素。