• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Biochemistry of irradiated parasite vaccines: suggested models for their mode of action.

作者信息

Wales A, Kusel J R

机构信息

Department of Biochemistry, University of Glasgow, Glasgow, UK G 12 8QQ.

出版信息

Parasitol Today. 1992 Nov;8(11):358-63. doi: 10.1016/0169-4758(92)90167-z.

DOI:10.1016/0169-4758(92)90167-z
PMID:15463538
Abstract

Irradiated larvae of a remarkably wide range of parasite species induce potent protective immunity against subsequent challenge of experimental hosts. Ann Wales and John Kusel have studied the irradiated cercariae of Schistosoma mansoni and suggest here that the effects of irradiation on conformation and presentation of parasite antigens may be crucial in enhancing parasite immunogenicity so effectively.

摘要

相似文献

1
Biochemistry of irradiated parasite vaccines: suggested models for their mode of action.
Parasitol Today. 1992 Nov;8(11):358-63. doi: 10.1016/0169-4758(92)90167-z.
2
Inhibition of protein synthesis in irradiated larvae of Schistosoma mansoni.
Parasite Immunol. 1992 Sep;14(5):513-30. doi: 10.1111/j.1365-3024.1992.tb00025.x.
3
Comparison of the vaccine efficacy of gamma-irradiated Schistosoma japonicum cercariae with the defined antigen Sj62(IrV-5) in pigs.γ射线辐照日本血吸虫尾蚴与特定抗原Sj62（IrV-5）在猪体内疫苗效力的比较
Vet Parasitol. 2001 Sep 12;100(1-2):51-62. doi: 10.1016/s0304-4017(01)00483-6.
4
Irradiation of Schistosoma mansoni cercariae impairs neuromuscular function in developing schistosomula.曼氏血吸虫尾蚴的照射会损害发育中血吸虫幼虫的神经肌肉功能。
J Parasitol. 1993 Apr;79(2):286-9.
5
Immunisation of baboons against Schistosoma mansoni using irradiated S. mansoni cercariae and schistosomula and non-irradiated S. rodhaini cercariae.使用经辐照的曼氏血吸虫尾蚴和童虫以及未经辐照的罗氏血吸虫尾蚴对狒狒进行曼氏血吸虫免疫接种。
J Helminthol. 1976 Sep;50(3):215-21. doi: 10.1017/s0022149x00027772.
6
Attempts to induce resistance in mice to Schistosoma japonicum and Schistosoma mansoni by exposure to crude schistosome antigens plus cloned glutathione-S-transferases.通过暴露于粗制血吸虫抗原加克隆的谷胱甘肽-S-转移酶来诱导小鼠对日本血吸虫和曼氏血吸虫产生抗性的尝试。
Immunol Cell Biol. 1990 Dec;68 ( Pt 6):377-85. doi: 10.1038/icb.1990.51.
7
Effects of irradiation on surface carbohydrates of larvae of Schistosoma mansoni.辐射对曼氏血吸虫幼虫表面碳水化合物的影响。
Parasitology. 1993 Feb;106 ( Pt 2):117-25. doi: 10.1017/s0031182000074916.
8
Mechanisms of protective immunity against Schistosoma mansoni infection in mice vaccinated with irradiated cercariae. IV. Analysis of the role of IgE antibodies and mast cells.用辐照尾蚴免疫的小鼠对曼氏血吸虫感染的保护性免疫机制。IV. IgE抗体和肥大细胞作用的分析
J Immunol. 1983 Sep;131(3):1460-5.
9
Schistosoma mansoni: identification and protective immunity of adult worm antigens recognized by T lymphocytes of outbred Swiss mice immunized with irradiated cercariae.曼氏血吸虫：用辐照尾蚴免疫远交系瑞士小鼠的T淋巴细胞所识别的成虫抗原的鉴定及保护性免疫
Exp Parasitol. 1993 May;76(3):265-77. doi: 10.1006/expr.1993.1032.
10
Comparison of Schistosoma mansoni irradiated cercariae and Sm23 DNA vaccines.曼氏血吸虫辐照尾蚴与Sm23 DNA疫苗的比较。
Parasite Immunol. 2005 Sep;27(9):341-9. doi: 10.1111/j.1365-3024.2005.00785.x.

引用本文的文献

1
Ultraviolet disinfection of Schistosoma mansoni cercariae in water.水中曼氏血吸虫尾蚴的紫外线消毒。
PLoS Negl Trop Dis. 2021 Jul 6;15(7):e0009572. doi: 10.1371/journal.pntd.0009572. eCollection 2021 Jul.
2
Evaluation of Heating and Irradiation Methods for Production of Purified Protein Derivative (PPD) of Mycobacterium Tuberculosis.结核分枝杆菌纯蛋白衍生物（PPD）生产中加热和辐照方法的评估
Arch Razi Inst. 2021 Jan;75(4):439-449. doi: 10.22092/ari.2019.123082.1238. Epub 2021 Jan 1.
3
Why the radiation-attenuated cercarial immunization studies failed to guide the road for an effective schistosomiasis vaccine: A review.
为何辐射减毒尾蚴免疫研究未能为有效血吸虫病疫苗指明道路：综述。
J Adv Res. 2015 May;6(3):255-67. doi: 10.1016/j.jare.2014.10.002. Epub 2014 Oct 20.
4
Therapy with radio-attenuated vaccine in experimental murine visceral leishmaniasis showed enhanced T cell and inducible nitric oxide synthase levels, suppressed tumor growth factor-beta production with higher expression of some signaling molecules.用减毒活疫苗治疗实验性小鼠内脏利什曼病显示T细胞和诱导型一氧化氮合酶水平增强，肿瘤生长因子-β产生受到抑制，一些信号分子表达升高。
Braz J Infect Dis. 2015 Jan-Feb;19(1):36-42. doi: 10.1016/j.bjid.2014.10.009. Epub 2014 Dec 19.
5
Ultrastructural changes of adult Schistosoma mansoni worms recovered from C57BL/6 mice passively immunized with normal and vaccinated rabbit sera in vivo.从体内用正常和接种疫苗的兔血清被动免疫的 C57BL/6 小鼠中回收的曼氏血吸虫成虫的超微结构变化。
Parasitol Res. 2012 Jan;110(1):37-47. doi: 10.1007/s00436-011-2448-7. Epub 2011 May 26.
6
Gamma radiation effects on Sporothrix schenckii yeast cells.伽马射线对申克孢子丝菌酵母细胞的影响。
Mycopathologia. 2011 Jun;171(6):395-401. doi: 10.1007/s11046-011-9395-9. Epub 2011 Feb 16.
7
Mice immunization with radioattenuated yeast cells of Paracoccidiodes brasiliensis: influence of the number of immunizations.用巴西副球孢子菌辐射减毒酵母细胞对小鼠进行免疫：免疫次数的影响
Mycopathologia. 2009 Aug;168(2):51-8. doi: 10.1007/s11046-009-9197-5. Epub 2009 Apr 7.
8
Schistosoma japonicum: proteomics analysis of differentially expressed proteins from ultraviolet-attenuated cercariae compared to normal cercariae.日本血吸虫：紫外线减毒尾蚴与正常尾蚴差异表达蛋白质的蛋白质组学分析
Parasitol Res. 2009 Jul;105(1):237-48. doi: 10.1007/s00436-009-1387-z. Epub 2009 Mar 17.