Suppr超能文献

单克隆抗体及其片段的生产技术。

Production technologies for monoclonal antibodies and their fragments.

作者信息

Andersen Dana C, Reilly Dorothea E

机构信息

Genentech, Inc, 1 DNA Way, South San Francisco, CA 94080, USA.

出版信息

Curr Opin Biotechnol. 2004 Oct;15(5):456-62. doi: 10.1016/j.copbio.2004.08.002.

Abstract

In recent years, monoclonal antibodies have emerged as an increasingly important class of human therapeutics. A variety of forms of antibodies, including fragments such as Fabs, Fab'2s and single-chain Fvs, are also being evaluated for a range of different purposes. A variety of expression systems and improvements within these systems have been developed to address these growing and diverse needs.

摘要

近年来,单克隆抗体已成为一类日益重要的人类治疗药物。包括Fab、Fab'2和单链Fv等片段在内的多种抗体形式也正在针对一系列不同目的进行评估。为满足这些不断增长的多样化需求,已开发出多种表达系统及对这些系统的改进方法。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验