Suppr超能文献

胸廓内动脉与桡动脉T型移植物的血流动力学

Flow dynamics of the internal thoracic and radial artery T-graft.

作者信息

Affleck David G, Barner Hendrick B, Bailey Marci S, Perry Loretta A, Maniar Hersh, Prasad Sunil M, Damiano Ralph J

机构信息

Division of Cardiothoracic Surgery, Washington University School of Medicine, St. Louis, Missouri 63110, USA.

出版信息

Ann Thorac Surg. 2004 Oct;78(4):1290-4; discussion 1290-4. doi: 10.1016/j.athoracsur.2004.03.113.

Abstract

BACKGROUND

Complex use of arterial conduits has resurrected concerns about the adequacy of conduit flow. The T-graft is the extreme example of this trend. Our purpose was to identify the limitation of single source inflow and to compare flow capacity with completion coronary flow.

METHODS

Between February 1999 and November 2001, 372 patients underwent total arterial revascularization with the T-graft alone. Intraoperative flows were recorded for each limb of the T-graft before and after distal anastomoses in 204 patients. Independent predictors of T-graft flow were identified by multivariate analysis.

RESULTS

Free flow for the radial arterial (RA) limb was 161 +/- 81 mL/min, the internal thoracic artery (ITA) limb 137 +/- 57 mL/min (combined 298 +/- 101 mL/min) versus simultaneous limb flow of 226 +/- 84 mL/min giving a flow restriction of 24% +/- 14%. Completion coronary flow was 88 +/- 49 mL/min for the RA, 60 +/- 45 mL/min for the ITA, and 140 +/- 70 mL/min for both limbs simultaneously to give a flow reserve (vs simultaneous free flow) of 160% or 1.6. Independent predictors of completion RA limb flow are RA proximal diameter (p = 0.005), number of anastomoses (p = 0.018), and target stenosis (p = 0.005).

CONCLUSIONS

A flow reserve of 1.6 compares favorably with an ITA flow reserve of 1.8 at 1-month postoperatively and 1.8 for both the ITA T-graft and the ITA/RA T-graft at 1-week postoperatively as reported by others. Proximal RA diameter and competitive coronary flow influence completion T-graft flow. These data quantitate the limitation of single source inflow of the T-graft configuration and support its continued use.

摘要

背景

动脉血管移植物的复杂应用再次引发了对移植物血流量充足性的担忧。T形移植物就是这种趋势的极端例子。我们的目的是确定单一来源血流的局限性,并将血流量与完全性冠状动脉血流进行比较。

方法

1999年2月至2001年11月期间,372例患者仅接受了T形移植物的全动脉血管重建术。对204例患者在远端吻合前后记录T形移植物各分支的术中血流。通过多变量分析确定T形移植物血流的独立预测因素。

结果

桡动脉(RA)分支的自由血流为161±81毫升/分钟,胸廓内动脉(ITA)分支为137±57毫升/分钟(两者合计为298±101毫升/分钟),而同时分支血流为226±84毫升/分钟,血流限制为24%±14%。RA的完全性冠状动脉血流为88±49毫升/分钟,ITA为60±45毫升/分钟,两者同时为140±70毫升/分钟,从而得出血流储备(相对于同时自由血流)为160%或1.6。完全性RA分支血流的独立预测因素为RA近端直径(p = 0.005)、吻合口数量(p = 0.018)和靶病变狭窄(p = 0.005)。

结论

1.6的血流储备与其他人报道的术后1个月时ITA的血流储备1.8以及术后1周时ITA T形移植物和ITA/RA T形移植物两者的血流储备1.8相比具有优势。RA近端直径和竞争性冠状动脉血流影响T形移植物的完全血流。这些数据量化了T形移植物构型单一来源血流的局限性,并支持其继续使用。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验