Rubio C A, Aberg B, Stemmermann G
Department of Pathology, Karolinska Institute, Stockholm, Sweden.
Acta Cytol. 1992 Jan-Feb;36(1):65-8.
Eighteen surgical specimens having an adenocarcinoma arising in Barrett's esophagus were reviewed, and special attention was paid to the presence of ciliated cells. The tumors were classified as glandular (9), papillary (4), diffuse (3) and mixed (2) types. Ciliated cells were observed in one specimen, in cystically dilated glands in Barrett's mucosa adjacent to a papillary adenocarcinoma. Ciliated tumor cells were found in three of the four papillary adenocarcinomas. The fourth papillary tumor, 1 mixed papillary-diffuse adenocarcinoma and the remaining 13 adenocarcinomas had no ciliated cells. Thus, the presence of cilia in exfoliated tumor cells from the esophagus should raise the suspicion of a papillary adenocarcinoma arising in Barrett's mucosa.
对18例起源于巴雷特食管的腺癌手术标本进行了回顾，并特别关注纤毛细胞的存在情况。这些肿瘤分为腺型（9例）、乳头型（4例）、弥漫型（3例）和混合型（2例）。在1例标本中观察到纤毛细胞，位于巴雷特黏膜中与乳头状腺癌相邻的囊性扩张腺体中。在4例乳头状腺癌中的3例发现了纤毛肿瘤细胞。第四例乳头状肿瘤、1例乳头-弥漫混合型腺癌以及其余13例腺癌均未发现纤毛细胞。因此，食管脱落肿瘤细胞中出现纤毛应引起对巴雷特黏膜中发生乳头状腺癌的怀疑。
