Luchetti Riccardo
Department of Plastic and Reconstructive Surgery and Hand Surgery, University of Ancona, Ancona, Italy.
J Hand Surg Am. 2004 Sep;29(5):825-34. doi: 10.1016/j.jhsa.2004.06.004.
The purpose of the present study was to report on the author's experience using carbonated hydroxyapatite as a bony substitute in distal radius corrective osteotomies.
Six patients had a corrective osteotomy for a malunited distal radius fracture using carbonated hydroxyapatite as an alternative to an autogenous bone graft. Internal fixation of the osteotomy was achieved by using 2 or 3 K-wires.
At an average follow-up evaluation of 33 months (range, 22-45 mo) all the osteotomies united. Wrist flexion-extension motion improved from 75 degrees to 110 degrees , forearm rotation increased from 116 degrees to 157 degrees , and grip strength had an average increase of 140% at the time of the final follow-up evaluation. All patients were satisfied and there were no reports of persistent pain. Radiographic evaluation showed an average volar tilt improvement from a preoperative dorsal angulation shifting into a neutral position in the sagittal plane; radial lengthening improved from an average of 4 mm (range, 2-6 mm) before surgery to 7 mm (range, 5-9 mm) after surgery, ulnar plus deformity improved by 5 mm. Radiographically the carbonated hydroxyapatite material was integrated completely into the bone tissue with evidence of progressive re-absorption and bony calcification over time. The Mayo wrist score system, according to Cooney and Krimmer modifications, improved by an average of 88 and 98 points (0-100 points), respectively.
On the basis of this preliminary experience it is reasonable to consider carbonated hydroxyapatite as a viable alternative to bone grafting in conjunction with surgical correction of a distal radius malunion. It must be augmented, however, with internal fixation.
本研究旨在报告作者使用碳酸羟基磷灰石作为桡骨远端截骨矫正术中骨替代物的经验。
6例患者因桡骨远端骨折畸形愈合接受截骨矫正术,使用碳酸羟基磷灰石替代自体骨移植。截骨处采用2根或3根克氏针进行内固定。
平均随访33个月(范围22 - 45个月),所有截骨均愈合。腕关节屈伸活动度从75度提高到110度,前臂旋转度从116度增加到157度,末次随访时握力平均增加140%。所有患者均满意,无持续性疼痛报告。影像学评估显示,矢状面平均掌倾角从术前的背侧成角改善为中立位;桡骨长度从术前平均4 mm(范围2 - 6 mm)增加到术后7 mm(范围5 - 9 mm),尺骨正偏畸形改善5 mm。影像学上,碳酸羟基磷灰石材料完全融入骨组织,随着时间推移有逐渐再吸收和骨钙化的迹象。根据库尼和克里默改良的梅奥腕关节评分系统,分别平均提高了88分和98分(0 - 100分)。
基于这一初步经验,在桡骨远端畸形愈合的手术矫正中,将碳酸羟基磷灰石视为骨移植的可行替代物是合理的。然而,必须辅以内固定。