使用医用粘合剂进行中小血管的无缝合吻合术。

Sutureless anastomoses of small and medium sized vessels by medical adhesive.

作者信息

Qu Lefeng, Jing Zaiping, Wang Yuqi

机构信息

Department of Vascular Surgery, Changhai Hospital, Second Military Medical University, Shanghai 200433, China.

出版信息

Eur J Vasc Endovasc Surg. 2004 Nov;28(5):526-33. doi: 10.1016/j.ejvs.2004.07.018.

DOI:10.1016/j.ejvs.2004.07.018

PMID:15465375

Abstract

PURPOSE

Using an animal model we have assessed sutureless anastomoses.

METHODS

The two cut ends of the rabbit common carotid artery were sutured by three stitches with a 120 degrees interval circumferentially, then two optional threads were pulled horizontally and 0.1 ml adhesive was smeared on the attached surface of the two ends. The three stitches were removed after completion of anastomosis. The burst pressure of the anastomosis was measured and compared with that of a traditional sutured artery.

RESULTS

The glued anastomosis was associated with: a shorter completion time (8.25+/-6.34 min vs. 20.67+/-14.24 min, P<0.01), less bleeding (3.17+/-9.04 ml vs. 11.04+/-16.28 ml, P<0.01), and equivalent patency (93.8 vs. 87.5%, P>0.05). The sutureless anastomosis was associated with less intimal thickening (decreased by 31.4, 24.5, 23.9 and 31.9%, P<0.01 compared with the traditional suture group at 1, 2, 4 and 12 weeks, respectively).

CONCLUSION

Glued anastomoses provides an effective, simple and feasible way for anastomosing small or medium caliber vessels. This technique may reduce intimal injury.

摘要

目的

我们使用动物模型评估了无缝合吻合术。

方法

将兔颈总动脉的两个断端沿圆周以120度间隔缝合三针，然后水平牵拉两根可选的线，并在两端的贴合面上涂抹0.1毫升粘合剂。吻合完成后拆除三针。测量吻合口的破裂压力，并与传统缝合动脉的破裂压力进行比较。

结果

粘合吻合术具有以下特点：完成时间更短（8.25±6.34分钟对20.67±14.24分钟，P<0.01），出血更少（3.17±9.04毫升对11.04±16.28毫升，P<0.01），通畅率相当（93.8%对87.5%，P>0.05）。无缝合吻合术内膜增厚较少（在第1、2、4和12周时，与传统缝合组相比分别减少31.4%、24.5%、23.9%和31.9%，P<0.01）。