A new lignan from Balanophora abbreviata and inhibition of lipopolysaccharide (LPS)-induced inducible nitric oxide synthase (iNOS) expression.
作者信息
Hosokawa Akihiro, Sumino Megumi, Nakamura Tomonori, Yano Shingo, Sekine Toshikazu, Ruangrungsi Nijsiri, Watanabe Kazuko, Ikegami Fumio
机构信息
Graduate School of Pharmaceutical Sciences, Chiba University, Japan.
出版信息
Chem Pharm Bull (Tokyo). 2004 Oct;52(10):1265-7. doi: 10.1248/cpb.52.1265.
PMID:15467252
Abstract
Six lignans including a new lignan (1), beta-sitosterol glucopyranoside and phenylpropanoids were isolated from the whole plants of Balanophora abbreviata Bl. (Balanophoraceae). Their structures were determined by NMR, MS analysis and other spectroscopic methods. Lignans (1, 2 and 4) showed potent inhibitory activities on the lipopolysaccharide (LPS)-induced inducible nitric oxide synthase (iNOS) expression in RAW 264.7 cells.
摘要
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