Kashiwagi K, Tokunaga T, Iwase A, Yamamoto T, Tsukahara S
Department of Ophthalmology, University of Yamanashi, Faculty of Medicine, Tamaho, Yamanashi, Japan.
Eye (Lond). 2005 Sep;19(9):990-4. doi: 10.1038/sj.eye.6701700.
This study was conducted to determine the usefulness of peripheral anterior chamber depth assessment in angle-closure glaucoma (ACG) screening in Japanese subjects.
The subjects were 14,779 adults 40 years old or older. Eyes having peripheral anterior chamber depth that is 1/4 the peripheral corneal thickness (van Herick's classification: grade 2) and less than 1/4 the peripheral corneal thickness (van Herick's classification: grade 1) were extracted as narrow angle eyes, and those eyes were further examined.
Of 14,779 subjects, 923 eyes of 505 subjects were diagnosed as narrow angle eyes (3.4%). Narrow angle eyes were observed in 4.9% of female subjects and 1.9% of male subjects, indicating a significantly higher frequency in women. The percentage of narrow angle eyes increased with age. Among the narrow angle eyes, 61 eyes of 32 subjects were diagnosed with ACG suspect (6.5%). In contrast to the frequency of ACG suspect in eyes classified as grade 1, according to van Herick's classification, being 17.9%, that in eyes classified as grade 2 was significantly lower at 5.6%.
Since the incidence of ACG suspect increases as the peripheral anterior chamber depth decreases, caution for the peripheral anterior chamber depth is required for the ACG screening.
本研究旨在确定周边前房深度评估在日本受试者闭角型青光眼(ACG)筛查中的有用性。
受试者为14779名40岁及以上的成年人。将周边前房深度为周边角膜厚度的1/4(van Herick分级:2级)及小于周边角膜厚度的1/4(van Herick分级:1级)的眼睛提取为窄角眼,并对这些眼睛进行进一步检查。
在14779名受试者中,505名受试者的923只眼睛被诊断为窄角眼(3.4%)。窄角眼在4.9%的女性受试者和1.9%的男性受试者中被观察到,表明女性中的频率显著更高。窄角眼的百分比随年龄增加。在窄角眼中,32名受试者的61只眼睛被诊断为ACG疑似病例(6.5%)。与根据van Herick分级分类为1级的眼睛中ACG疑似病例的频率17.9%相比,分类为2级的眼睛中的频率显著更低,为5.6%。
由于随着周边前房深度的减小,ACG疑似病例的发生率增加,因此在ACG筛查中需要注意周边前房深度。