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儿童白血病中伴草绿色链球菌败血症的肌炎

Myositis complicating viridans streptococcal sepsis in childhood leukemia.

作者信息

Sandlund John T, Howard Scott C, Hijiya Nobuko, Pui Ching-Hon, Shenep Jerry L, Adderson Elisabeth E

机构信息

Department of Hematology-Oncology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.

出版信息

Pediatr Blood Cancer. 2005 Mar;44(3):277-9. doi: 10.1002/pbc.20225.

Abstract

Hematogenous focal infections are a rare complication of bacteremia or sepsis caused by viridans-group streptococci. We describe two patients with acute leukemia who developed myositis during alpha-hemolytic streptococcal bacteremia. Children complaining of severe muscle pain associated with viridans streptococcal infections should be carefully evaluated for the presence of focal pyogenic complications and rhabdomyolysis. The severity of infectious myositis is highly variable, depending on the etiologic organism and host immunity, making individualized treatment the most effective approach.

摘要

血源性局灶性感染是由草绿色链球菌引起的菌血症或败血症的一种罕见并发症。我们描述了两名急性白血病患者,他们在甲型溶血性链球菌菌血症期间发生了肌炎。对于主诉与草绿色链球菌感染相关的严重肌肉疼痛的儿童,应仔细评估是否存在局灶性化脓性并发症和横纹肌溶解症。感染性肌炎的严重程度差异很大,取决于病原体和宿主免疫力,因此个体化治疗是最有效的方法。

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