Aminuddin B S
Tissue Engineering Laboratory, Hospital Universiti Kebangsaan Malaysia, Ear, Nose & Throat Consultant Clinic, Ampang Puteri Specialist Hospital Kuala Lumpur, Malaysia.
Med J Malaysia. 2004 May;59 Suppl B:3-4.
Management of severe tracheal anomalies remains a clinical challenge. Tissue engineering offers new hope in trachea reconstruction surgery. However to date no optimal technique achieved in the formation of human or animal trachea. The main problem lies on the biomaterial used and the complex city of forming trachea in vivo. This study was aimed at creating tissue-engineered trachea cartilage from easily accessible human and animal nasal septum cartilage using internal scaffold and biodegradable human and animal fibrin.
严重气管异常的管理仍然是一项临床挑战。组织工程为气管重建手术带来了新的希望。然而，迄今为止，在人类或动物气管形成方面尚未实现最佳技术。主要问题在于所使用的生物材料以及在体内形成气管的复杂性。本研究旨在利用内部支架和可生物降解的人类及动物纤维蛋白，从易于获取的人类和动物鼻中隔软骨中创建组织工程气管软骨。
