Huang Zhi-Gang, Han De-Min, Yu Zhen-Kun, Ni Xin, Chen Xiao-Hong
Department of Otorhinolarynology Head and Neck Surgery, Beijing Tongren Hospital, Affiliated to Capital University of Medical Sciences, Beijing 100730, China.
Zhonghua Er Bi Yan Hou Ke Za Zhi. 2004 Jul;39(7):399-401.
To explore the security and limit resection extension of CO2 laser surgery for laryngeal cancer in experimental animal under self-retaining laryngoscope.
Ten experimental dogs were selected and received CO2 laser surgery with self-retaining laryngoscope. Vertical partial or supraglottic horizontal laryngectomy was performed according to the surgical criteria. All the dogs were killed immediately (5/10) or 40 days later(5/10) by using air embolus postoperatively. The whole larynx was taken out, and specimens were embedded with colloidion and then serially sectioned. Dimension of excision and wound surface recovery status were observed.
All the operations on experiment animals were successful and the results were satisfactory. The excision dimension was the same as standard surgery. Gross specimens and serial sectioning staining of 5 dogs were performed. And the other 5 dogs wound surface had already recovered.
CO2 laser surgery was comparable with traditional vertical partial laryngectomy and supraglottic horizontal laryngectomy for excision size. Animals were able to survive the surgery, wound surface could recover spontaneously. It suggested the possibility of extended laryngectomy with laser.
探讨在支撑喉镜下二氧化碳激光手术治疗实验动物喉癌的安全性及切除范围的局限性。
选取10只实验犬，在支撑喉镜下行二氧化碳激光手术。根据手术标准行垂直部分喉切除术或声门上水平喉切除术。术后所有犬分别于术后即刻（5/10）或40天后（5/10）采用空气栓塞法处死。取出全喉，标本用火棉胶包埋后连续切片。观察切除范围及创面愈合情况。
所有实验动物手术均成功，效果满意。切除范围与标准手术相同。对5只犬进行大体标本及连续切片染色观察，另外5只犬创面已愈合。
二氧化碳激光手术在切除范围方面与传统垂直部分喉切除术和声门上水平喉切除术相当。动物能够耐受手术，创面可自行愈合。提示了激光扩大喉切除术的可能性。
