Guittet Lydia, Blaisdell Carol J, Just Jocelyne, Rosencher Lise, Valleron Alain-Jacques, Flahault Antoine
Inserm U444 and Hôpital Tenon, Paris, France.
Br J Gen Pract. 2004 Oct;54(507):759-64.
General practitioners (GPs) have a central place in the management of asthma, particularly in the context of acute exacerbations.
To evaluate the management of asthma exacerbations by GPs, and to investigate the ability of risk factors for near fatal asthma to predict the severity of asthma attacks in the community.
A 1-month multicentre cross-sectional survey.
One thousand and ninety-four GPs of the French Sentinel Network were contacted; 365 responded.
Asthma exacerbations were classified according to severity at presentation. Univariate and multivariate analyses were performed by logistic regression to identify those factors associated with severe exacerbations.
Exacerbations were described in 219 patients with asthma. Over half (54%) of exacerbations were severe. Peak expiratory flow was recorded during the consultation in 55% of patients who were more than 5 years old. beta(2) agonists were prescribed to 93% of patients, systemic corticosteroids to 71%, and antibiotics to 64%. Only 42% of patients had a written action plan for self-management of exacerbations. Risk factors for near fatal asthma, identified in 26% of patients, were not significantly associated with severe asthma exacerbations. Short duration of exacerbation before consultation (<3 hours) was associated with an increase in relative risk of severe exacerbation of 3.38, 95% confidence intervals (CIs) = 1.19 to 9.61, compared with duration of >3 hours.
Risk factors for near fatal asthma identified in previous studies were not predictive of a severe exacerbation in general practice, with the exception of short duration of exacerbation before consultation. This suggests that new methods to predict risk in the outpatient settings should be developed.
全科医生(GPs)在哮喘管理中占据核心地位,尤其是在急性加重的情况下。
评估全科医生对哮喘加重的管理,并调查近乎致命哮喘的危险因素预测社区哮喘发作严重程度的能力。
为期1个月的多中心横断面调查。
联系了法国哨点网络的1094名全科医生;365人做出了回应。
根据就诊时的严重程度对哮喘加重进行分类。通过逻辑回归进行单变量和多变量分析,以确定与严重加重相关的因素。
219例哮喘患者出现了加重情况。超过一半(54%)的加重情况为严重加重。55%的5岁以上患者在就诊时记录了呼气峰值流速。93%的患者使用了β2激动剂,71%使用了全身糖皮质激素,64%使用了抗生素。只有42%的患者有哮喘加重自我管理的书面行动计划。26%的患者被确定为有近乎致命哮喘的危险因素,这些因素与严重哮喘加重无显著关联。与就诊前加重持续时间>3小时相比,就诊前加重持续时间短(<3小时)与严重加重相对风险增加3.38相关,95%置信区间(CIs)=1.19至9.61。
除就诊前加重持续时间短外,先前研究中确定的近乎致命哮喘的危险因素在全科医疗中不能预测严重加重情况。这表明应开发新的方法来预测门诊环境中的风险。