Higes Pascual F, Rubio Esteban G, García Guijo C, Pascual Martín-Gamero M L, Liaño Martínez H
Servicio de Neurología, Clínica Puerta de Hierro, Madrid.
Rev Esp Enferm Dig. 1992 Jan;81(1):49-51.
We report a case of anorectal melanoma, whose first manifestation was a carcinomatous meningitis. The anorectal melanoma is a rare tumor of great malignity which represents 1-3 per cent of melanomas and 0.5 per cent of anorectal tumors. The most frequent symptoms are non-specific: rectal bleeding, pain at defecation, changes in the intestinal rythm. Sixty per cent of cases presented metastasis at the moment of diagnosis limited to the regional lymph nodes. In none of the cases published did the metastasis present as the first symptom. The case presented here manifested itself only with neurologic symptomatology compatible with carcinomatous meningitis whose finding led to the search of the original tumor, and this is what makes this case exceptional since the infrequency of this tumor is united to an unusual clinical presentation, not previously described in the literature.
我们报告一例肛门直肠黑色素瘤,其首发表现为癌性脑膜炎。肛门直肠黑色素瘤是一种罕见的高恶性肿瘤,占黑色素瘤的1%-3%,占肛门直肠肿瘤的0.5%。最常见的症状是非特异性的:直肠出血、排便时疼痛、肠道节律改变。60%的病例在诊断时出现转移,局限于区域淋巴结。在已发表的病例中,均无转移作为首发症状。此处报告的病例仅表现为与癌性脑膜炎相符的神经症状,该症状促使对原发肿瘤进行查找,这使得该病例不同寻常,因为这种肿瘤罕见且临床表现不常见,此前文献中未曾描述过。