Cleaton-Jones P, Duggal M, Parak R, Williams S, Setzer S
Medical Research Council/University of the Witwatersrand Dental Research Institute, Johannesburg, South Africa.
Eur J Paediatr Dent. 2004 Sep;5(3):131-5.
To compare histological responses to zinc oxide-eugenol (ZOE) and calcium hydroxide (CH) pulpectomies in primary molar teeth with inflamed pulps.
This was an experimental study in 17 juvenile baboons (Papio ursinus).
Pulpitis was induced with fresh human carious dentine or Streptococcus mutans placed into occlusal cavities in 78 primary molars; after 14 days a pulpectomy was performed on the same primary molars with the two root fillings randomly allocated. The root canal openings were then covered with IRM and the cavity filled with amalgam. After 90 days specimens were harvested and examined under the light microscope with the examiner blind to the treatment.
Reaction frequencies in the ZOE-treated versus CH-treated teeth were: no recognisable pulp 89% and 82%, internal root resorption 0% and 1%, external root resorption 11% and 24%, presence of bacteria 5% and 18%, periapical abscesses 24% and 52%.
Fisher's exact probability test showed a statistically significant higher prevalence of periapical abscesses in the CH-treated group (P=0.03, relative risk 2.2).
ZOE pulpectomy is preferred to CH for the treatment of infected pulps in primary molars.
比较氧化锌丁香酚（ZOE）和氢氧化钙（CH）对患有炎症牙髓的乳磨牙进行牙髓摘除术后的组织学反应。
这是一项针对17只幼年狒狒（山魈）的实验研究。
用新鲜的人类龋坏牙本质或变形链球菌诱导78颗乳磨牙的牙髓炎，将其置于咬合面龋洞中；14天后，对同一批乳磨牙进行牙髓摘除术，并随机分配两种根管充填材料。然后用IRM覆盖根管口，并用汞合金充填窝洞。90天后采集标本，在光学显微镜下检查，检查者对治疗情况不知情。
ZOE治疗组与CH治疗组的反应频率分别为：无可识别的牙髓89%和82%，牙根内吸收0%和1%，牙根外吸收11%和24%，有细菌5%和18%，根尖脓肿24%和52%。
Fisher精确概率检验显示，CH治疗组根尖脓肿的患病率在统计学上显著更高（P = 0.03，相对风险2.2）。
对于乳磨牙感染牙髓的治疗，ZOE牙髓摘除术优于CH。
Zotero 插件