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旋毛虫病的临床症状、诊断与治疗

Clinical aspects, diagnosis and treatment of trichinellosis.

作者信息

Pozio Edoardo, Gomez Morales Maria Angeles, Dupouy-Camet Jean

机构信息

Laboratory of Parasitology, Istituto Superiore di Sanità, Viale Regina Elena 299, 00161 Rome, Italy.

出版信息

Expert Rev Anti Infect Ther. 2003 Oct;1(3):471-82. doi: 10.1586/14787210.1.3.471.

Abstract

Trichinellosis, the human disease induced by worms of the genus Trichinella, is caused by the consumption of raw or undercooked meat of various types of animals and has a worldwide prevalence of approximately eleven million. Since there are no pathognomonic signs or symptoms, clinical diagnosis is difficult and the only reliable diagnostic methods are serodiagnosis and muscle biopsy. Treatment consists of benzimidazoles and glucocorticosteroids, yet in order for these drugs to be effective, they must be administered before the end of the acute stage; thus early diagnosis is fundamental. To aid in the recognition and treatment of trichinellosis, an overall description of its clinical aspects, diagnosis and treatment has been prepared.

摘要

旋毛虫病是由旋毛虫属的蠕虫引起的人类疾病,它是因食用各种动物的生肉或未煮熟的肉而引发的,在全球范围内的患病率约为1100万。由于没有特征性的体征或症状,临床诊断困难,唯一可靠的诊断方法是血清学诊断和肌肉活检。治疗方法包括使用苯并咪唑类药物和糖皮质激素,然而,为使这些药物有效,必须在急性期结束前给药;因此,早期诊断至关重要。为了帮助识别和治疗旋毛虫病,已对其临床症状、诊断和治疗进行了全面描述。

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