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超重和肥胖的初级保健患者中高血压非常普遍且控制不佳。

Hypertension in overweight and obese primary care patients is highly prevalent and poorly controlled.

作者信息

Bramlage Peter, Pittrow David, Wittchen Hans-Ulrich, Kirch Wilhelm, Boehler Steffen, Lehnert Hendrik, Hoefler Michael, Unger Thomas, Sharma Arya M

机构信息

Institute of Clinical Pharmacology, Institute of Clinical Psychology and Psychotherapy, Technical University, Dresden. peter,

出版信息

Am J Hypertens. 2004 Oct;17(10):904-10. doi: 10.1016/j.amjhyper.2004.05.017.

Abstract

BACKGROUND

Although the relationship between body weight and blood pressure (BP) is well established, there is a lack of data regarding the impact of obesity on the prevalence of hypertension in primary care practice. The objective of this study was to assess the prevalence of hypertension and the diagnosis, treatment status, and control rates of hypertension in obese patients as compared to patients with normal weight.

METHODS

A cross-sectional point prevalence study of 45,125 unselected consecutive primary care attendees was conducted in a representative nationwide sample of 1912 primary care physicians in Germany (HYDRA).

RESULTS

Blood pressure levels were consistently higher in obese patients. Overall prevalence of hypertension (blood pressure >/=140/90 mm Hg or on antihypertensive medication) in normal weight patients was 34.3%, in overweight participants 60.6%, in grade 1 obesity 72.9%, in grade 2 obesity 77.1%, and in grade 3 obesity 74.1%. The odds ratio (OR) for good BP control (<140/90 mm Hg) in diagnosed and treated patients was 0.8 (95% confidence interval [CI] 0.7-0.9) in overweight patients, 0.6 (95% CI 0.6-0.7) in grade 1, 0.5 (95% CI 0.4-0.6) in grade 2, and 0.7 (95% CI 0.5-0.9) in grade 3 obese patients.

CONCLUSIONS

The increasing prevalence of hypertension in obese patients and the low control rates in overweight and obese patients document the challenge that hypertension control in obese patients imposes on the primary care physician. These results highlight the need for specific evidence-based guidelines for the pharmacologic management of obesity-related hypertension in primary practice.

摘要

背景

尽管体重与血压(BP)之间的关系已得到充分证实,但在初级保健实践中,关于肥胖对高血压患病率影响的数据却很缺乏。本研究的目的是评估肥胖患者与正常体重患者相比高血压的患病率以及高血压的诊断、治疗状况和控制率。

方法

在德国1912名初级保健医生的具有代表性的全国性样本中,对45125名未经选择的连续初级保健就诊者进行了横断面现患率研究(HYDRA)。

结果

肥胖患者的血压水平始终较高。正常体重患者中高血压(血压≥140/90 mmHg或正在服用抗高血压药物)的总体患病率为34.3%,超重参与者为60.6%,1级肥胖者为72.9%,2级肥胖者为77.1%,3级肥胖者为74.1%。在已诊断和治疗的患者中,超重患者血压良好控制(<140/90 mmHg)的优势比(OR)为0.8(95%置信区间[CI]0.7 - 0.9),1级肥胖者为0.6(95%CI 0.6 - 0.7),2级肥胖者为0.5(95%CI 0.4 - 0.6),3级肥胖者为0.7(95%CI 0.5 - 0.9)。

结论

肥胖患者中高血压患病率不断上升,超重和肥胖患者的控制率较低,这表明肥胖患者的高血压控制给初级保健医生带来了挑战。这些结果凸显了在初级实践中针对肥胖相关高血压的药物管理制定具体循证指南的必要性。

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