Evaluation of tests based on the antibody response to keyhole limpet haemocyanin and soluble egg antigen to differentiate acute and chronic human schistosomiasis mansoni.

作者信息

Beck Lílian, Van-Lüme Daniele S M, Souza Joelma R de, Morais Clarice N Lins de, Melo Wlademir G, Xavier Edeneide, Barbosa Constança S, Aroucha Marcílio L, Domingues Ana Lúcia C, Favre Tereza, Pieri Otávio, Abath Frederico G C, Montenegro Silvia M L

机构信息

Instituto Oswaldo Cruz-Fiocruz, Rio de Janeiro, RJ, Brazil.

出版信息

Mem Inst Oswaldo Cruz. 2004;99(5 Suppl 1):97-8. doi: 10.1590/s0074-02762004000900017. Epub 2004 Oct 13.

Specific IgG and IgM responses to soluble egg antigen (SEA) and keyhole limpet haemocyanin (KLH) were measured by ELISA in patients with acute and chronic schistosomiasis. The tests based upon IgM and IgG antibodies responses to KLH presented the best diagnostic discrimination, and can be used in conjunction with clinical and epidemiological data to the differential diagnosis of acute schistosomiasis.