Lambert S R, Lynn M, Drews-Botsch C, DuBois L, Plager D A, Medow N B, Wilson M E, Buckley E G
Emory University School of Public Health, Atlanta, GA, USA.
Br J Ophthalmol. 2004 Nov;88(11):1387-90. doi: 10.1136/bjo.2004.045609.
To compare optotype acuities and re-operation rates in children corrected with a contact lens (CL) compared with an intraocular lens (IOL) following unilateral cataract extraction during infancy in a non-randomised, retrospective case series.
25 infants with a unilateral congenital cataract underwent cataract surgery with (IOL group, n = 12) or without (CL group, n = 13) IOL implantation when <7 months of age. Optotype acuities were assessed in 19 of these children at a mean age of 4.3 years (range 3.3-5.5 years). The number of re-operations were assessed in 21 children.
The visual acuity results were similar in the two treatment groups (p = 0.99); however, two of the four (50%) children in the IOL group compared with two of the seven (28%) children in the CL group undergoing surgery during the first 6 weeks of life had 20/40 or better visual acuity. The children in the IOL group had more re-operations than the children in the CL group (mean 1.1 v 0.36). Most of the re-operations in the IOL group were membranectomies performed during the first year of life (median 8.0 months) whereas all of the re-operations in the CL group were the implantation of a secondary IOL later in childhood (mean 2.2 years).
Optotype acuities were similar for the children corrected with a CL compared with IOL, while the children in the IOL group underwent more re-operations .
在一个非随机、回顾性病例系列中,比较婴儿期单侧白内障摘除术后接受角膜接触镜(CL)矫正与人工晶状体(IOL)矫正的儿童的视标视力和再次手术率。
25例单侧先天性白内障婴儿在7个月龄之前接受了白内障手术,其中12例植入IOL(IOL组),13例未植入IOL(CL组)。在这些儿童中,19例在平均年龄4.3岁(范围3.3 - 5.5岁)时接受了视标视力评估。对21例儿童的再次手术次数进行了评估。
两个治疗组的视力结果相似(p = 0.99);然而,在出生后前6周接受手术的IOL组4名儿童中有2名(50%)视力达到20/40或更好,而CL组7名儿童中有2名(28%)达到该视力。IOL组儿童的再次手术次数比CL组儿童多(平均1.1次对0.36次)。IOL组的大多数再次手术是在出生后第一年(中位时间8.0个月)进行的膜切除术,而CL组的所有再次手术都是在儿童后期(平均2.2岁)植入二期IOL。
与IOL矫正的儿童相比,CL矫正的儿童视标视力相似,但IOL组儿童接受的再次手术更多。